%0 Journal Article %A Marshall, Jonathon J. A. %A Fayard, Blandine %A Roy, Polly %T Biophysical Studies on the Morphology of Baculovirus-expressed Bluetongue Virus Tubules %D 1990 %J Journal of General Virology, %V 71 %N 8 %P 1839-1844 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-71-8-1839 %I Microbiology Society, %X Bluetongue virus tubules were purified from Spodop- tera frugiperda cells infected with a recombinant baculovirus containing the NS 1 gene from bluetongue virus serotype 10, and expressed under control of the Autographa californica nuclear polyhedrosis virus polyhedrin promoter. These tubules were subjected to a variety of chemical and physical treatments and the resulting effects on tubule morphology were examined by electron microscopy. A number of morphological similarities were noted between bluetongue virus tubules and cellular microtubules despite a lack of homology between the component proteins at the primary sequence level. A possible multistranded helical configuration is proposed for the tubule structure. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-71-8-1839