1887

Abstract

The nucleotide sequence was determined for the fusion (F) protein-coding mRNA of the bovine respiratory syncytial virus (strain RB 94) and the amino acid sequence of the F protein was deduced for comparison with the sequence of human respiratory syncytial virus subtypes A and B (RSS-2 and 18537 strains). The human and bovine RS virus F proteins (excluding the cleaved signal peptide) share 83 to 84% homology. The greatest divergence occurred within the F2 subunit in the region preceding the cleavage activation site.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-71-12-3009
1990-12-01
2024-04-25
Loading full text...

Full text loading...

/deliver/fulltext/jgv/71/12/JV0710123009.html?itemId=/content/journal/jgv/10.1099/0022-1317-71-12-3009&mimeType=html&fmt=ahah

References

  1. Anderson L. J., Hierholzer J. C., Tsos C., Hendry R. M., Fernie B. F., Stone Y., Macintosh K. 1985; Antigenic characterization of respiratory syncytial virus strains with mono-clonal antibodies. Journal of Infectious Diseases 151:626–633
    [Google Scholar]
  2. Arumugham R. G., Seid R. C., Doyle J. S., Hildreth S. W., Paradiso P. R. 1989; Fatty acid acylation of the fusion glycoprotein of human respiratory syncytial virus. Journal of Biological Chemistry 264:10339–10342
    [Google Scholar]
  3. Austen B. M. 1979; Predicted secondary structures of amino- terminal extension sequences of secreted proteins. FEBS Letters 103:308–313
    [Google Scholar]
  4. Baybutt H. N., Pringle C. R. 1987; Molecular cloning and sequencing of the F and 22K membrane protein genes of the RSS-2 strain of respiratory syncytial virus. Journal of General Virology 68:2789–2796
    [Google Scholar]
  5. Cash P., Wunner W. H., Pringle C. R. 1977; A comparison of the polypeptides of human and bovine respiratory syncytial viruses and murine pneumonia virus. Virology 82:369–379
    [Google Scholar]
  6. Collins P. L., Huang Y. T., Wertz G. W. 1984; Nucleotide sequence of the gene encoding the fusion (F) glycoprotein of human respiratory syncytial virus. Proceedings of the National Academy of Sciences, U.S.A 81:7683–7687
    [Google Scholar]
  7. Gimenez H. B., Hardman N., Kier H. M., Cash P. 1986; Antigenic variation between human respiratory syncytial virus isolates. Journal of General Virology 67:863–870
    [Google Scholar]
  8. Johnson P. R., Collins P. L. 1988; The fusion glycoproteins of human respiratory syncytial virus of subgroups A and B: sequence conservation provides a structural basis for antigenic relatedness. Journal of General Virology 69:2623–2628
    [Google Scholar]
  9. Johnson P. R., Olmsted R. A., Prince G. A., Murphy B. R., Alling B. W., Walsh E. E., Collins P. L. 1987; Antigenic relatedness between the glycoproteins of human respiratory syncytial virus subgroups A and B: evaluation of the contribution of the F and G glycoproteins to immunity. Journal of Virology 61:3163–3166
    [Google Scholar]
  10. Kennedy H. E., Jones B. V., Tucker E. M., Ford N. J., Clarke S. W., Furze J., Thomas L. H., Stott E. J. 1988; Production and characterization of monoclonal antibodies to respiratory syncytial virus. Journal of General Virology 69:3023–3032
    [Google Scholar]
  11. Le L., Brasseur R., Wemers C., Meulemans G., Burny A. 1988; Fusion (F) protein gene of Newcastle disease virus: sequence hydrophobicity comparative analysis between virulent and avirulent strains. Virus Genes 4:333–350
    [Google Scholar]
  12. Lerch R. A., Stott E. J., Wertz G. W. 1989; Characterization of bovine respiratory syncytial virus proteins and mRNAs and generation of cDNA clones to the viral mRNAs. Journal of Virology 63:833–840
    [Google Scholar]
  13. Levine S., Klaiber-Franco R., Paradiso P. R. 1987; Demonstration that glycoprotein G is the attachment protein of respiratory syncytial virus. Journal of General Virology 68:2521–2524
    [Google Scholar]
  14. Lopez J. A., Villanueva N., Melero J. A., Portella A. 1988; Nucleotide sequence of the fusion and phosphoprotein genes of human respiratory syncytial (RS) virus Long strain: evidence of subtype heterogeneity. Virus Research 10:249–262
    [Google Scholar]
  15. Lopez J. A., Penas C., Garcia-Barreno B., Melero J. A., Portella A. 1990; Location of a highly conserved neutralizing epitope in the F glycoprotein of human respiratory syncytial virus. Journal of Virology 64:927–930
    [Google Scholar]
  16. Matsumoto M., Inaba Y., Kurogi H., Sato K., Omori T., Goto Y., Hirose O. 1974; Bovine respiratory syncytial virus: host range in laboratory animals and cell culture. Archiv für die gesamte Virusforschung 44:280–290
    [Google Scholar]
  17. Morrison T. G. 1988; Structural, function and intracellular processing of paramyxovirus membrane proteins. Virus Research 10:113–136
    [Google Scholar]
  18. Mufson M. A., Örvell C., Rafnar B., Norrby E. 1985; Two distinct subtypes of human respiratory syncytial virus. Journal of General Virology 66:2111–2124
    [Google Scholar]
  19. Olmsted R. A., Elango N., Prince G. A., Murphy B. R., Johnson P. R., Moss B., Chanock R. M., Collins P. L. 1986; Expression of the F glycoprotein of respiratory syncytial virus by a recombinant vaccinia virus: comparison of the individual contributions of the F and G glycoprotein to host immunity. Proceedings of the National Academy of Sciences, U.S.A 83:7462–7466
    [Google Scholar]
  20. Örvell C., Norrby E., Mufson M. A. 1987; Preparation and characterization of monoclonal antibodies directed against five structural components of human respiratory syncytial virus subgroup B. Journal of General Virology 68:3125–3135
    [Google Scholar]
  21. Paccaud M. F., Jacquier C. 1970; A respiratory syncytial virus of bovine origin. Archiv für die gesamte Virusforschung 30:327–342
    [Google Scholar]
  22. Pringle C. R. 1985; Pneumoviruses. In Virology, A Practical Approach pp. 95–117 Mahy B. W. J. Edited by Oxford: IRL Press;
    [Google Scholar]
  23. Sanger F., Nicklen S., Coulson A. R. 1977; DNA sequencing with chain terminating inhibitors. Proceedings of the National Academy of Sciences, U.S.A 74:5463–5467
    [Google Scholar]
  24. Scheid A., Choppin P. W. 1974; Identification and biological activities of paramyxovirus glycoproteins: activation of cell fusion, hemolysis and infectivity by proteolytic cleavage of an inactive precursor protein of Sendaï virus. Virology 57:475–490
    [Google Scholar]
  25. Schmidt M. F. G., Lambrecht B. 1985; On the structure of the acyl linkage and function of fatty acyl chains in the influenza virus haemagglutinin and the glycoproteins of Semliki Forest virus. Journal of General Virology 66:2635–2647
    [Google Scholar]
  26. Scopes G. E., Watt P. J., Lambden P. R. 1990; Identification of a linear epitope on the fusion glycoprotein of respiratory syncytial virus. Journal of General Virology 71:53–59
    [Google Scholar]
  27. Stott E. J., Taylor G. 1985; Respiratory syncytial virus. Brief review. Archives of Virology 84:1–52
    [Google Scholar]
  28. Taylor G., Stott E. J., Bew M., Fernie B. F., Cote P. J., Collins A. P., Hughes M., Jebbett J. 1984; Monoclonal antibodies protect against respiratory syncytial virus infection in mice. Immunology 52:137–142
    [Google Scholar]
  29. Trudel M., Nadon F., Seguin C., Dionne G., Lacroix M. 1987; Identification of a synthetic peptide as part of a major neutralization epitope of respiratory syncytial virus. Journal of General Virology 68:2273–2280
    [Google Scholar]
  30. Trudel M., Nadon F., Sinnard C., Belanger F., Alain R., Seguin C., Lussier G. 1989; Comparison of caprine, human and bovine strains of respiratory syncytial virus. Archives of Virology 107:141–149
    [Google Scholar]
  31. Walsh E. E., Hruska J. F. 1983; Monoclonal antibodies to respiratory syncytial virus proteins; identification of the fusion protein. Journal of Virology 47:171–177
    [Google Scholar]
  32. Walsh E. E., Brandriss M. W., Schlesinger J. J. 1985; Purification and characterization of the respiratory syncytial virus fusion protein. Journal of General Virology 66:409–415
    [Google Scholar]
  33. Walsh E. E., Cote P. J., Fernie B. F., Schlesinger J. J., Brandriss M. W. 1986; Analysis of the respiratory syncytial virus fusion protein using monoclonal and polyclonal antibodies. Journal of General Virology 67:505–513
    [Google Scholar]
  34. Wellemans G., Leunen J. 1975; Le virus respiratoire syncitialet les troubles respiratoire des bovins. Annales de médecine vétérinaire 119:359–369
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-71-12-3009
Loading
/content/journal/jgv/10.1099/0022-1317-71-12-3009
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error