RT Journal Article SR Electronic(1) A1 Ogura, Hisashi A1 Sato, Hiroshi A1 Kamiya, Shigeru A1 Nakamura, ShinichiYR 1990 T1 Temperature elevation enhances cell surface expression of measles virus fusion protein in infected cells JF Journal of General Virology, VO 71 IS 10 SP 2475 OP 2478 DO https://doi.org/10.1099/0022-1317-71-10-2475 PB Microbiology Society, SN 1465-2099, AB Cell fusion proceeded gradually in measles virus-infected cells incubated at 35 °C. Shift-up of incubation temperature to 39 °C induced rapidly increased cell fusion in spite of the cessation of de novo synthesis of the fusion (F) protein. Pulse-chase experiments showed that there was little difference in the acquisition of immunoreactivity by haemagglutinin (H) and F proteins between the two temperatures. H protein was detected on the cell surface 60 min after the chase at either temperature. However, appearance of F protein on the cell surface took less than 3 h at 39 °C whereas it took 5 h at 35 °C. These data indicate that temperature elevation induces more efficient expression of F protein on the cell surface accompanied by marked syncytium formation in measles virus-infected cells., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-71-10-2475