A synthetic peptide elicits antibody reactive with the native duck hepatitis B virus pre-S protein Free

Abstract

Synthetic peptides P37–49 and P63–79, derived from the pre-S region of duck hepatitis B virus (DHBV), have been synthesized. Only P37–49 was reactive with rabbit anti-DHBs/pre-S antibodies by radioimmuno-precipitation. Antiserum prepared against P37–47 reacted with a 35K polypeptide of native DHBs/pre-S by immunoblotting. It is concluded that P37–49 (MGQHPAKSMDVRR) mimics one of the epitopes of the DHBV pre-S antigen.

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1990-10-01
2024-03-29
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