1887

Abstract

Summary

Seven temperature-sensitive (ts) mutants of Abelson murine leukaemia virus (A-MuLV) were isolated on the basis of the temperature dependence of their soft agar colony-forming ability. These seven ts mutants exhibited similar characteristics and were not ts for morphological transformation and autophosphorylation of P120 protein. The dissociation of the properties of morphology, soft agar colony formation and tyrosine kinase activity might suggest that the v- product has more than one primary intracellular target.

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/content/journal/jgv/10.1099/0022-1317-70-9-2527
1989-09-01
2024-04-25
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