1887

Abstract

SUMMARY

There is a significant difference in the ability of human influenza A virus H1N1 strains isolated up to 1977 and those isolated later to rescue temperature-sensitive mutants of fowl plague virus with a defect in the nucleoprotein (NP) gene. Therefore the NP genes of five human H1N1 and H3N2 influenza A virus strains, isolated between 1950 and 1978, have been sequenced. By comparison with previous and more recent isolates, an evolutionary pathway has been established. Three amino acid replacements were found which might be responsible for the functional difference between the USSR (1977) and the Brazil (1978) strains. The California (H1N1) strain isolated in 1978 had acquired by reassortment the NP gene of a human H3N2 virus circulating at about 1977 as had been previously suggested by investigations involving RNase fingerprint or hybridization techniques.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-70-8-2111
1989-08-01
2022-08-11
Loading full text...

Full text loading...

/deliver/fulltext/jgv/70/8/JV0700082111.html?itemId=/content/journal/jgv/10.1099/0022-1317-70-8-2111&mimeType=html&fmt=ahah

References

  1. Bean W. J. 1980; Recombination of human influenza A viruses in nature. Nature London: 284638–640
    [Google Scholar]
  2. Becht H., Malole B. 1975; Comparative evaluation of different fixation procedures and different coupling reagents for the demonstration of influenza virus-specific antibodies by the indirect hemagglutination test. Medical Microbiology and Immunology 162:43–53
    [Google Scholar]
  3. Both G. W., Sleigh M. I., Cox N. J., Kendal A. P. 1983; Antigenic drift in influenza virus H3 hemagglutinin from 1968 to 1980: multiple evolutionary pathways and sequential amino acid changes of key antigenic sites. Journal of Virology 48:52–60
    [Google Scholar]
  4. Buckler-white A. J., Murphy B. R. 1986; Nucleotide sequence analysis of the nucleoprotein gene of an avianand a human influenza virus strain identifies two classes of nucleoproteins. Virology 155:345–355
    [Google Scholar]
  5. Buonagurio D. A., Nakada S., Parvin J. D., Krystal M., Palese P., Fitch W. M. 1986; Evolution of human influenza A viruses over 50 years: rapid, uniform rate of change in NS gene. Science 232:980–982
    [Google Scholar]
  6. Cox N. J., Kitame F., Kendal A. P., Maassab H. F., Naeve C. 1988; Identification of sequence changes in the cold adapted, life attenuated influenza vaccine strain, A/Ann Arbor/6/60 (H2N2). Virology 167:554–567
    [Google Scholar]
  7. Fitch W. M. 1971; Towards defining the course of evolution: minimum change for a specific tree topology. Systematic Zoology 20:406–416
    [Google Scholar]
  8. Gammelin M., Mandler J., Scholtissek C. 1989; Two subtypes of nucleoptoteins (NP) of influenza A viruses. Virology 170:71–80
    [Google Scholar]
  9. Huddleston J. A., Brownlee G. G. 1982; The sequence of the nucleoprotein gene of human influenza A virus strain A/NT/60/68. Nucleic Acids Research 10:1029–1038
    [Google Scholar]
  10. Kendal A. P., Noble G. R., Skehel J. J., Dowdle W. R. 1978; Antigenic similarity of influenza A (H1N1) viruses from epidemics in 1977–1978 to “Scandinavian” strains isolated in epidemics of 1950–1951. Virology 89:632–636
    [Google Scholar]
  11. Maniatis T., Fritsch E. F., Sambrook J. 1982 Molecular Cloning: A Laboratory Manual New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  12. Nakajima K., Desselberger U., Palese P. 1978; Recent human influenza A viruses are closely related genetically to strains isolated in 1950. Nature, London 274:334–339
    [Google Scholar]
  13. Raymond F. L., Caton A. J., Cox N. J., Kendal A. P., Brownlee G. G. 1983; Antigenicity and evolution amongst recent influenza viruses of H1N1 subtype. Nucleic Acids Research 11:7191–7203
    [Google Scholar]
  14. Raymond F. L., Caton A. J., Cox N. I., Kendal A. P., Brownlee G. G. 1986; The antigenicity and evolution of influenza HI haemagglutinins, from 1950–1957 and 1977–1983: two pathways from one gene. Virology 148275–287
    [Google Scholar]
  15. Sanger F., Nicklen S., Coulson A. R. 1977; DNA sequencing with chain-terminating inhibitors. Proceedings of the National Academy of SciencesU.S.A 74:5463–5467
    [Google Scholar]
  16. Scholtissek C., Bowles L. A. 1975; Isolation and characterization of temperature-sensitive mutants of fowl plague virus. Virology 67:576–587
    [Google Scholar]
  17. Scholtissek C, Harms E., Rohde W., Orlich M., Rott R. 1976; Correlation between RNA fragments of fowl plague virus and their corresponding gene functions. Virology 74:332–344
    [Google Scholar]
  18. Scholtissek C, Von hoyningen V., Rott R. 1978a; Genetic relatedness between the new 1977 epidemic strain (H1N1) of influenza and human influenza strains isolated between 1947 and 1957 (H1N1). Virology 89:613–617
    [Google Scholar]
  19. Scholtissek C., Koennecke I., Rott R. 1978b; Host range recombinants of fowl plague (influenza A) virus. Virology 91:79–85
    [Google Scholar]
  20. Scholtissek C., Rohde W., Von hoyningen V., Rott R. 1978c; On the origin of the human influenza virus subtypes H2N2 and H3N3. Virology 87:13–20
    [Google Scholar]
  21. Scholtissek C, Burger H., Kistner O., Shortridge K. F. 1985; The nucleoprotein as a possible major factor in determining host specificity of influenza H3N2 viruses. Virology 147:287–294
    [Google Scholar]
  22. Snyder M. H., Buckler-White A. J., London W. T., Tierney E. L., Murphy B. R. 1987; The avian influenza virus nucleoprotein gene and a specific constellation of avian and human virus polymerase genes each specify attenuation of avian-human influenza A/pintail/79 reassortant viruses for monkeys. Journal of Virology 61:2857–2863
    [Google Scholar]
  23. Tomley F. M., Roditi I. I. 1984; Nucleotide sequence of RNA segment 5, encoding the nucleoprotein of influenza A/FPV/Rostock/34. Virus Research 1:625–630
    [Google Scholar]
  24. Winter G., Fields S. 1981; The structure of the gene encoding the nucleoprotein of human influenza virus A/PR/8/34. Virology 113:423–428
    [Google Scholar]
  25. Young J. E., Palese P. 1979; Evolution of human influenza A viruses in nature: recombination contributes to genetic variation of H1N1 strains. Proceedings of the National Academy of SciencesU.S.A 76:6547–6551
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-70-8-2111
Loading
/content/journal/jgv/10.1099/0022-1317-70-8-2111
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error