Structure and Expression of an Integrated Human Papillomavirus Type 16 Genome Amplified in a Cervical Carcinoma Cell Line

Hiroshi Shirasawa; Yoshimi Tomita; Akira Fuse; Tomoko Yamamoto; Hideki Tanzawa; Souei Sekiya; Hiroyoshi Takamizawa; Bunsiti Simizu

doi:10.1099/0022-1317-70-7-1913

Structure and Expression of an Integrated Human Papillomavirus Type 16 Genome Amplified in a Cervical Carcinoma Cell Line

Hiroshi Shirasawa, Yoshimi Tomita, Akira Fuse, Tomoko Yamamoto, Hideki Tanzawa, Souei Sekiya, Hiroyoshi Takamizawa and Bunsiti Simizu
First Published: 01 July 1989 https://doi.org/10.1099/0022-1317-70-7-1913

Abstract

Summary

A cellular sequence containing the integrated human papillomavirus type 16 genome in a cervical carcinoma cell line QG-U was cloned and analysed. The transcriptionally active viral genome disrupted at the E2 and L2 open reading frames was amplified with its flanking sequences.

Received: 05/12/1988
Accepted: 17/02/1989
Published Online: 01/07/1989

Keyword(s): cervical carcinoma cell line , flanking sequences and HPV-16 genome

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1989-07-01

2019-11-15

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Journal of General Virology

Volume 70, Issue 7

Research Article

Free

Structure and Expression of an Integrated Human Papillomavirus Type 16 Genome Amplified in a Cervical Carcinoma Cell Line

Abstract

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