Structure and Expression of an Integrated Human Papillomavirus Type 16 Genome Amplified in a Cervical Carcinoma Cell Line

Hiroshi Shirasawa; Yoshimi Tomita; Akira Fuse; Tomoko Yamamoto; Hideki Tanzawa; Souei Sekiya; Hiroyoshi Takamizawa; Bunsiti Simizu

doi:10.1099/0022-1317-70-7-1913

Structure and Expression of an Integrated Human Papillomavirus Type 16 Genome Amplified in a Cervical Carcinoma Cell Line

Hiroshi Shirasawa, Yoshimi Tomita, Akira Fuse, Tomoko Yamamoto, Hideki Tanzawa, Souei Sekiya, Hiroyoshi Takamizawa and Bunsiti Simizu
First Published: 01 July 1989 https://doi.org/10.1099/0022-1317-70-7-1913

Abstract

Summary

A cellular sequence containing the integrated human papillomavirus type 16 genome in a cervical carcinoma cell line QG-U was cloned and analysed. The transcriptionally active viral genome disrupted at the E2 and L2 open reading frames was amplified with its flanking sequences.

Received: 05/12/1988
Accepted: 17/02/1989
Published Online: 01/07/1989

Keyword(s): cervical carcinoma cell line , flanking sequences and HPV-16 genome

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-70-7-1913

1989-07-01

2021-02-26

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-70-7-1913

Journal of General Virology

Volume 70, Issue 7

Research Article

Free

Structure and Expression of an Integrated Human Papillomavirus Type 16 Genome Amplified in a Cervical Carcinoma Cell Line

Abstract

Most read this month

Most cited this month Most Cited RSS feed

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

Updated classification of norovirus genogroups and genotypes

Characteristics of the Microplate Method of Enzyme-Linked Immunosorbent Assay for the Detection of Plant Viruses

The dynamics of humoral immune responses following SARS-CoV-2 infection and the potential for reinfection

The Complete DNA Sequence of the Long Unique Region in the Genome of Herpes Simplex Virus Type 1

Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment

ICTV Virus Taxonomy Profile: Geminiviridae

Mechanisms and enzymes involved in SARS coronavirus genome expression

The use of general primers GP5 and GP6 elongated at their 3′ ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR

ICTV Virus Taxonomy Profile: Flaviviridae