RT Journal Article SR Electronic(1) A1 Sinclair, R. A1 Cook, R. F. A1 Mumford, J. A.YR 1989 T1 The Characterization of Neutralizing and Non-neutralizing Monoclonal Antibodies against Equid Herpesvirus Type 1 JF Journal of General Virology, VO 70 IS 2 SP 455 OP 459 DO https://doi.org/10.1099/0022-1317-70-2-455 PB Microbiology Society, SN 1465-2099, AB SUMMARY Seven monoclonal antibodies (MAbs) were produced which recognized equid herpesvirus type 1 (EHV-1). Three MAbs neutralized the subtype 1 virus (strain Army 183) in the presence of complement, but did not neutralize the subtype 2 virus (strain MD). All three MAbs immunoprecipitated an M r 83K glycoprotein from a detergent-solubilized virion envelope preparation of the subtype 1 virus. The target antigens of the four non-neutralizing MAbs (6F11, 2A4, 1F10 and 8D9) were identified by immunoblotting against purified EHV-1 virions and had respective apparent M r values of > 205K, > 205K, 97K and 13K., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-70-2-455