1887

Abstract

SUMMARY

Monoclonal antibodies were produced against two comoviruses, cowpea mosaic virus and cowpea severe mosaic virus. The antibodies were tested for their recognition of coat proteins of each virus in various conformational states by enzyme-linked immunosorbent assays. Three groups of epitopes were identified on the basis of antibody binding to native or denatured virions. Antibodies specific for epitopes exposed only after virus denaturation were cross-reactive, recognizing both viruses. Antibodies binding epitopes of the other two groups recognized intact virions and varied in their degree of cross-reactivity.

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/content/journal/jgv/10.1099/0022-1317-70-12-3451
1989-12-01
2022-01-20
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