%0 Journal Article %A MacLean, Christine A. %A Clark, Billy %A McGeoch, Duncan J. %T Gene UL11 of Herpes Simplex Virus Type 1 Encodes a Virion Protein which Is Myristylated %D 1989 %J Journal of General Virology, %V 70 %N 12 %P 3147-3157 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-70-12-3147 %K myristylation %K gene UL11 %K HSV-1 %I Microbiology Society, %X SUMMARY We have investigated whether herpes simplex virus (HSV) contains structural polypeptides which are modified by myristic acid. We demonstrate that herpes simplex virions contain a family of myristylated proteins, M r approximately 13000 to 16000. These were mapped, using HSV-1/HSV-2 intertypic recombinants, to 0·130 to 0·204 map units on the virus genome. Using anti-peptide sera, raised against the carboxy-terminus of the predicted UL11 gene product, we have established that the myristylated virion polypeptides are products of the viral gene UL11. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-70-12-3147