@article{mbs:/content/journal/jgv/10.1099/0022-1317-69-6-1391, author = "Gruenberg, A. and Woo, W. S. and Biedrzycka, A. and Wright, Peter J.", title = "Partial Nucleotide Sequence and Deduced Amino Acid Sequence of the Structural Proteins of Dengue Virus Type 2, New Guinea C and PUO-218 Strains", journal= "Journal of General Virology", year = "1988", volume = "69", number = "6", pages = "1391-1398", doi = "https://doi.org/10.1099/0022-1317-69-6-1391", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-69-6-1391", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "structural proteins", keywords = "dengue virus", keywords = "flavivirus cDNA", abstract = "Summary The nucleotide sequence and the deduced amino acid sequence for the genes encoding the structural proteins of two strains of dengue virus type 2 (DEN-2) were determined from cDNA clones. The genes for C, prM(M) and E proteins were sequenced for the prototype DEN-2 virus, the New Guinea C strain. Also sequenced were the prM(M) and E genes of PUO-218. This strain of DEN-2 was isolated during 1980 in Bangkok and had received a limited number of laboratory passages. Comparisons of the newly determined sequences with those published for the Jamaica 1409 and Puerto Rico PR-159 (S1 vaccine candidate) strains revealed a close relationship between New Guinea C virus and both the Jamaica and PUO-218 viruses (greater than 96% similarity in nucleotides of the E gene), whereas S1 virus was the most divergent.", }