RT Journal Article SR Electronic(1) A1 Rydbeck, Robert A1 Löve, Arthur A1 Norrby, ErlingYR 1988 T1 Protective Effects of Monoclonal Antibodies against Parainfluenza Virus Type 3-induced Brain Infection in Hamsters JF Journal of General Virology, VO 69 IS 5 SP 1019 OP 1024 DO https://doi.org/10.1099/0022-1317-69-5-1019 PB Microbiology Society, SN 1465-2099, AB Summary A collection of monoclonal antibodies (MAbs) against the haemagglutinin—neuraminidase (HN) and fusion (F) glycoproteins of parainfluenza virus type 3 (PIV3) was used for passive immunization of intracerebrally infected newborn hamsters. A significant degree of protection was obtained with MAbs against both the HN and F viral proteins, but no individual antibody conferred complete protection against disease. MAbs against different epitopes provided different degrees of protection. A MAb to the Sendai virus HN protein was found to confer protection against PIV3 brain infection., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-69-5-1019