1887

Journal of General Virology header logo

Volume 69, Issue 2

Canine Parvovirus: Strain Difference in Haemagglutination Activity and Antigenicity Free

Abstract

Summary

Canine parvovirus (CPV) strains were compared for haemagglutination (HA) activity and antigenicity and were divided into two types by HA activity. Strains Cp49 and 29-F showed temperature-dependent HA, like feline panleukopenia virus (FPLV) and mink enteritis virus (MEV), whereas strains Sp-80 and Y-1 showed temperature-independent HA with erythrocytes from eight species of animals. The results of a cross HA inhibition test using immunized rat sera suggested that of the two types of CPV those showing temperature-dependent HA were antigenically like FPLV and MEV whereas those showing temperature-independent HA were not. This antigenic difference between the two types was confirmed by a HA inhibition test with monoclonal antibodies. A chronological survey revealed that CPV isolates from earlier years have HA activity and antigenicity similar to those of FPLV and MEV, whereas current CPV isolates do not. There are some exceptional isolates from the transitional period which have similar antigenicity to FPLV and MEV but different HA activity. These results suggest that the haemagglutinin of CPV altered from one form resembling that of FPLV to a somewhat different structure during passage in dogs in nature.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): CPV , HA activity and strain difference
© Society for General Microbiology 1988
Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-69-2-349
1988-02-01
2024-04-20
Loading full text...

Full text loading...

/deliver/fulltext/jgv/69/2/JV0690020349.html?itemId=/content/journal/jgv/10.1099/0022-1317-69-2-349&mimeType=html&fmt=ahah

References

  1. APPEL M. J. G., SCOTT F. W., CARMICHAEL L. E. 1979; Isolation and immunisation studies of a canine parvo-like virus from dogs with haemorrhagic enteritis. Veterinary Record 105:156–159
     [Google Scholar]
  2. CARMICHAEL L. E., BINN L. N. 1981; New enteric viruses in the dog. Advances in Veterinary Science and Comparative Medicine 25:1–37
     [Google Scholar]
  3. CARMICHAEL L.E., JAUBERT J. C., POLLOCK R. V. H. 1980; Hemagglutination by canine parvovirus: serologic studies and diagnostic applications. American Journal of Veterinary Research 41:784–791
     [Google Scholar]
  4. FLOWER R. L. P., WILCOX G. E., ROBINSON W. F. 1980; Antigenic differences between canine parvovirus and feline panleukopenia virus. Veterinary Record 107:254–256
     [Google Scholar]
  5. GAGNON A. N., POVEY R. C. 1979; A possible parvovirus associated with an epidemic gastroenteritis of dogs in Canada. Veterinary Record 104:263–264
     [Google Scholar]
  6. GOTO H., YACHIDA S., SHIRAHATA T., SHIMIZU K. 1974; Feline panleukopenia in Japan. I. Isolation and characterization of the virus. Japanese Journal of Veterinary Science 36:203–211
     [Google Scholar]
  7. GOTO H., HIRANO T., UCHIDA E., WATANABE K., SHINAGAWA M., ICHIJO S., SHIMIZU K. 1984; Comparative studies of physicochemical and biological properties between canine parvovirus and feline panleukopenia virus. Japanese Journal of Veterinary Science 46:519–526
     [Google Scholar]
  8. HIGASHIHARA T., IZAWA H., ONUMA M., KODAMA H., MLKAMI T. 1981; Mink enteritis Japan. I. Isolation and characterization of the causative virus and its pathogenicity in cat. Japanese Journal of Veterinary Science 43:841–851
     [Google Scholar]
  9. JOHNSON R. H., SPRADBROW P. B. 1979; Isolation from dogs with severe enteritis of a parvovirus related to feline panleukopenia virus. Australian Veterinary Journal 55:151
     [Google Scholar]
  10. KONISHI S., MOCHIZUKI M., OGATA M. 1975; Studies on feline panleukopenia. I. Isolation and properties of virus strains. Japanese Journal of Veterinary Science 37:439–449
     [Google Scholar]
  11. LENGHAUS C., STUDDERT M.J. 1980; Relationship of canine panleukopenia (enteritis) and myocarditis parvoviruses to feline panleukopenia virus. Australian Veterinary Journal 56:152–153
     [Google Scholar]
  12. MOHRI A., HANDA S., WADA T. 1982; Sero-epidemiologic survey on canine parvovirus infection. Japanese Journal of Veterinary Science 44:543–545
     [Google Scholar]
  13. MORAILLON A., MORAILLON R. 1982; Distinction des parvovirus fé1ins et canins par hémagglutination. Recueil de médecine vétérinaire 158:799–804
     [Google Scholar]
  14. OSTERHAUS A. D. M. E., VAN STEENIS G., DE KREEK P. 1980; Isolation of a virus closely related to feline panleukopenia virus from dogs with diarrhea. Zentralblatt für Veterin5ärmedizin B 27:11–21
     [Google Scholar]
  15. PARRISH C. R., CARMICHAEL L. E. 1983; Antigenic structure and variation of canine parvovirus type-2, feline panleukopenia virus, and mink enteritis virus. Virology 129:401–414
     [Google Scholar]
  16. PARRISH C. R., CARMICHAEL L.E., ANTCZAK D. F. 1982; Antigenic relationships between canine parvovirus type-2, feline panleukopenia virus and mink enteritis virus using conventional antisera and monoclonal antibodies. Archives of Virology 72:267–278
     [Google Scholar]
  17. PARRISH C. R., O’CONNELL P. H., EVERMANN J. F., CARMICHAEL L. E. 1985; Natural variation of canine parvovirus. Science 230:1046–1048
     [Google Scholar]
  18. SENDA M., HIRAYAMA N., YAMAMOTO H., KURATA K. 1986; An improved hemagglutination test for study of canine parvovirus. Veterinary Microbiology 12:1–6
     [Google Scholar]
  19. TRATSCHIN J.-D., McMASTER G. K., KRONAUER G., SIEGL G. 1982; Canine parvovirus: relationship to wild-type and vaccine strains of feline panleukopenia virus and mink enteritis virus. Journal of General Virology 61:33–41
     [Google Scholar]
  20. WALKER S. T., FEILEN C. P., SABINE M., LOVE D. N., JONES R. F. 1980; A serological survey of canine parvovirus infection. Veterinary Record 106:324–325
     [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-69-2-349
Loading
Canine Parvovirus: Strain Difference in Haemagglutination Activity and Antigenicity
J. Gen. Virol. 69, 349 (1988); https://doi.org/10.1099/0022-1317-69-2-349
/content/journal/jgv/10.1099/0022-1317-69-2-349
/content/journal/jgv/10.1099/0022-1317-69-2-349
Loading

Data & Media loading...

Most cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error