1887

Abstract

SUMMARY

The p28 core polypeptides of four isolates of caprine arthritis-encephalitis virus (CAEV) from goats was compared with those of visna virus (VV) and progressive pneumonia virus (PPV) from sheep. Monoclonal antibodies recognized p28 epitopes common to all six retrovirus isolates, a p28 epitope on four CAEV isolates, but not VV and PPV isolates, a p28 epitope on four CAEV isolates and VV, but not PPV and a p28 epitope unique to the CAEV isolate used for immunizing the mouse spleen donor. Comparison of two-dimensional maps of tyrosine containing tryptic peptides of p28 demonstrated that three CAEV isolates had similar maps while a fourth CAEV isolate, VV and PPV had several peptides different from the three closely related CAEV p28s and from each other.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-68-8-2259
1987-08-01
2022-08-16
Loading full text...

Full text loading...

/deliver/fulltext/jgv/68/8/JV0680082259.html?itemId=/content/journal/jgv/10.1099/0022-1317-68-8-2259&mimeType=html&fmt=ahah

References

  1. Banks K. L., Adams D. S., McGuire T. C., Carlson J. L. 1983; Experimental infection of sheep by caprine arthritis-encephalitis virus and goats by progressive pneumonia virus. American Journal of Veterinary Research 44:2307–2311
    [Google Scholar]
  2. Cheevers W. P., Roberson S., Klevjer-Anderson P., Crawford T. B. 1981; Characterization of caprine arthritis-encephalitis virus: a retrovirus of goats. Archives of Virology 67:111–117
    [Google Scholar]
  3. Chuat J.-C., Grce M., Pilon C., Guillemin M.-C. 1985; Monoclonal antibodies to murine retrovirus protein p30. Journal of General Virology 66:1855–1862
    [Google Scholar]
  4. Cork L. C., Narayan O. 1980; The pathogenesis of viral leukoencephalitis-arthritis of goats. I. Persistent viral infection with progressive pathological changes. Laboratory Investigation 42:596–602
    [Google Scholar]
  5. Crawford T. B., Adams D. S., Cheevers W. P., Cork L. C. 1980; Chronic arthritis in goats caused by a retrovirus. Science 207:997–999
    [Google Scholar]
  6. Cutlip R. C., Lehmkuhl H. D., Brodgen K. A., Brolin S. R. 1985; Mastitis associated with ovine progressive pneumonia virus infection in sheep. American Journal of Veterinary Research 46:326–328
    [Google Scholar]
  7. Dahlberg J. E., Gaskin J. M., Perk K. 1981; Morphological and immunological comparison of caprine arthritis encephalitis and ovine progressive pneumonia viruses. Journal of Virology 39:914–919
    [Google Scholar]
  8. Davis W. C., Perryman L. E., McGuire T. C. 1983; The identification and analysis of major functional populations of differentiated cells. In Hybridoma Technology in Agriculture and Veterinary Research pp 121–150 Stem N. J., Gamble H. R. Edited by Totowa: Rowman & Allanheld;
    [Google Scholar]
  9. Elder J. H., Pickett R. A., Hampton J., Lerner R. A. 1977; Radioiodination of proteins in single polyacrylamide gel slices. Tryptic peptide analysis of all major members of complex multicomponent systems using microgram quantities of total protein. Journal of Biological Chemistry 252:6510–6515
    [Google Scholar]
  10. Gautsch J. W., Elder J. H., Schindler L, Jensen F. C., Lerner R. A. 1978; Structural markers on core protein p30 of murine leukemia virus : functional correlation with Fv-1 tropism. Proceedings of the National Academy of Sciences U.S.A.: 754170–4174
    [Google Scholar]
  11. Gazit A., Yaniv A., Dvir M., Perk K., Irving S. G., Dahlberg J. E. 1983; The caprine arthritis-encephalitis virus is a distinct virus within the lentivirus group. Virology 124:192–195
    [Google Scholar]
  12. Gogolewski R. P., Adams D. S., McGuire T. C., Banks K. L., Cheevers W. P. 1985; Antigenic cross-reactivity between caprine arthritis-encephalitis, visna and progressive pneumonia viruses involves all virion- associated proteins and glycoproteins. Journal of General Virology 66:1233–1240
    [Google Scholar]
  13. Gudnadottir M. 1974; Visna-Maedi in sheep. Progress in Medical Virology 18:336–349
    [Google Scholar]
  14. Johnson G. C., Barbet A. F., Klevjer-Anderson P., McGuire T. C. 1983; Preferential immune response to virion surface glycoproteins by caprine arthritis-encephalitis virus-infected goats. Infection and Immunity 41:657–665
    [Google Scholar]
  15. Jurkiewicz E., Nakamura H., Schneider J., Yamamoto N., Hayami M., Hunsmann G. 1986; Structural analysis of pl9 and p24 core polypeptides of primate lymphotropic retroviruses (PLRV). Virology 150:291–298
    [Google Scholar]
  16. Montelaro R. C., Parekh R., Orrego A., Issel C. J. 1984; Antigenic variation during persistent infection by equine infectious anemia virus, a retrovirus. Journal of Biological Chemistry 259:10539–10544
    [Google Scholar]
  17. Oliver R. E., Gorham J. R., Parish S. F., Hadlow W. J. 1981; Ovine progressive pneumonia: pathologic and virologie studies on the naturally occurring disease. American Journal of Veterinary Research 42:1554–1559
    [Google Scholar]
  18. Pyper J. M., Clements J. E., Gonda M. A., Narayan O. 1986; Sequence homology between cloned caprine arthritis encephalitis virus and visna virus, two neurotropic lentiviruses. Journal of Virology 58:665–670
    [Google Scholar]
  19. Roberson S. M., Mcguire T. C., Klevjer-Anderson P., Gorham J. R., Cheevers W. P. 1982; Caprine arthritis-encephalitis virus is distinct from visna and progressive pneumonia viruses as measured by genome sequence homology. Journal of Virology 44:754–757
    [Google Scholar]
  20. Weiss M. J., Zeelon E. P., Sweet R. W., Harter D. H., Spiegelman S. 1977; Immunological cross-reactions of the major internal protein component from ‘slow’ viruses of sheep. Virology 76:851–854
    [Google Scholar]
  21. Whittaker R. G., Moss B. A. 1981; Comparative peptide mapping at the nanomole level. Analytical Biochemistry 11:56–60
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-68-8-2259
Loading
/content/journal/jgv/10.1099/0022-1317-68-8-2259
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error