1887

Abstract

Summary

We have defined the boundaries of the sequence from human cytomegalovirus (CMV) strain Towne, characterized internal variability and determined the position of the cleavage site used to generate genomic termini. The cleavage site is positioned a fixed distance from two stretches of sequence homology that have been observed near the ends of many herpesvirus genomes. Unlike a comparable region in CMV (AD169), the CMV (Towne) sequence has a relatively low level of variability within the sequence and its structure is stable through repeated virus passage.

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/content/journal/jgv/10.1099/0022-1317-68-8-2223
1987-08-01
2019-11-18
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-68-8-2223
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