1887

Abstract

SUMMARY

In whole foetus D cells infected with feline infectious peritonitis virus (FIPV), strain 79–1146, six virus-specific, poly(A)-containing RNA species of about 20, 9·6, 5·2, 3·8, 2·8 and 1·6 kb were found. By translation the 3·8 and 2·8 kb RNAs were shown to encode the 25K envelope protein and the 45K nucleocapsid protein, respectively. The partial map of the FIPV genome was compared with genomic maps of porcine, murine and avian coronaviruses. Differences in these maps suggest that transcription units have been lost or gained during coronavirus divergence.

Keyword(s): coding assignment , FIPV and RNAs
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1987-04-01
2022-09-25
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References

  1. Armstrong J., Smeekens S., Spaan W., Rottier P., Van Der Zeijst B. A. M. 1984; Cloning and sequencing the nucleocapsid and El genes of coronavirus. In Molecular Biology and Pathogenesis of Coronaviruses pp 173–186 Rottier P. J. M., Van der Zeijst B. A. M., Spaan W. J. M., Horzinek M. C. Edited by New York: Plenum Press;
    [Google Scholar]
  2. Binns M. M., Boursnell M. E. G., Cavanagh D., Pappin D. J. C., Brown T. D. K. 1985; Cloning and sequencing of the gene encoding the spike protein of the coronavirus IBV. Journal of General Virology 66:719–726
    [Google Scholar]
  3. Boursnell M. E. G., Brown T. D. K. 1984; Sequencing of coronavirus IBV genomic RNA: a 195 base open reading frame encoded by mRNA B. Gene 29:87–92
    [Google Scholar]
  4. Boursnell M. E. G., Brown T. D. K., Binns M. M. 1984; Sequenceofthe membrane protein gene from avian coronavirus IBV. Virus Research 1:303–313
    [Google Scholar]
  5. Boursnell M. E. G., Binns M. M., Foulds I. J., Brown T. D. K. 1985a; Sequences of the nucleocapsid genes from two strains of avian infectious bronchitis virus. Journal of General Virology 66:573–580
    [Google Scholar]
  6. Boursnell M. E. G., Binns M. M., Brown T. D. K. 1985b; Sequencing of coronavirus IBV genomic RNA: three open reading frames in the 5′ ‘unique’ region of mRNA D. Journal of General Virology 66:2253–2258
    [Google Scholar]
  7. Boyle J. F., Pedersen N. C., Evermann J. F., Mckeirnan A. J., Ott R. L., Black J. W. 1984; Plaque assay, polypeptide composition and immunochemistry of feline infectious peritonitis virus and feline enteric coronavirus isolates. Advances in Experimental Medicine and Biology 173:133–147
    [Google Scholar]
  8. Brown T. D. K., Boursnell M. E. G., Binns M. M. 1984; Λ leader sequence is present on mRNΛ A of avian infectious bronchitis virus. Journal of General Virology 65:1437–1442
    [Google Scholar]
  9. Evermann J. F., Baumgartner L., Ott R. L., Davis E. v., Mckeirnan A. i. 1981; Characterization of a feline infectious peritonitis virus isolate. Veterinary Pathology 18:256–265
    [Google Scholar]
  10. Horzinek M. C., Osterhaus A. D. M. E. 1979; The virology and pathogenesis of feline infectious peritonitis. Brief review. Archives of Virology 59:1–15
    [Google Scholar]
  11. Horzinek M. C., Lutz H., Pedersen N. C. 1982; Antigenic relationships among homologous structural polypeptides of porcine, feline and canine coronaviruses. Infection and Immunity 37:1148–1155
    [Google Scholar]
  12. Hu S., Bruszewski J., Boone T., Souza L. 1984; Cloning and expression of the surface glycoprotein gpl95 of porcine transmissible gastroenteritis virus. In Modern Approaches to Vaccines pp 219–223 Chanock R. M., Lerner R. A. Edited by New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  13. Jacobs L., Van Der Zeijst B. A. M., Horzinek M. C. 1986; Characterization and translation of transmissible gastroenteritis virus mRNAs. Journal of Virology 57:1–6
    [Google Scholar]
  14. Jacobse-Geels H. E. L., Daha M. R., Horzinek M. C. 1980; Isolation and characterization of feline c3 and evidence for the immune complex pathogenesis of feline infectious peritonitis. Journal of Immunology 125:1606–1610
    [Google Scholar]
  15. Jacobse-Geels H. E. L., Daha M. R., Horzinek M. C. 1982; Antibody, immune complexes, and complement activity fluctuations in experimental feline infectious peritonitis. American Journal of Veterinary Research 43:666–670
    [Google Scholar]
  16. Lai M. M. C., Patton C. D., Stohlman S. A. 1982; Replication of mouse hepatitis virus: negative-stranded RNA and replicative form RNA are of genome length. Journal of Virology 44:487–492
    [Google Scholar]
  17. Lai M. M. C., Baric R. S., Brayton P. R., Stohlman S. A. 1984; Characterization of leader RNA sequences on the virion and mRNAs of mouse hepatitis virus, a cytoplasmic RNA virus. Proceedings of the National Academy of Sciences U.S.A: 813626–3630
    [Google Scholar]
  18. Mckeirnan A. J., Evermann J. F., Hargis A., Ott R. L. 1981; Isolation of feline coronaviruses from two cats with diverse disease manifestations. Feline Practice 11:17–20
    [Google Scholar]
  19. Mcmaster G. K., Carmichael G. G. 1977; Analyses of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. Proceedings of the National Academy of Sciences U.S.A: 744835–4838
    [Google Scholar]
  20. Pedersen N. C. 1983; Feline infectious peritonitis and feline enteric coronavirus infections. Feline Practice 13:5–20
    [Google Scholar]
  21. Pedersen N. C., Boyle J. F. 1980; Immunologic phenomena in the effusive form of feline infectious peritonitis. American Journal of Veterinary Research 41:868–876
    [Google Scholar]
  22. Pedersen N. C., Ward J., Mengeling W. L. 1978; . Antigenic relationship of the feline infectious peritonitis virus to coronaviruses of other species, Archives of Virology 58:45–53
    [Google Scholar]
  23. Rottier P. J. M., Spaan W. J. M., Horzinek M. C., Van Der Zeijst B. A. M. 1981; Translation of three mouse hepatitis virus strain A59 subgenomic RNAs inXenopus laevisoocytes. Journal of Virology 38:20–26
    [Google Scholar]
  24. Siddell S. 1983; Coronavirus JHM: coding assignments of subgenomic mRNAs. Journal of General Virology 64:113–125
    [Google Scholar]
  25. Siddell S. G., Wege H., Termeulen V. 1982; The structure and replication of coronaviruses. Current Topics in Microbiology and Immunology 99:131–163
    [Google Scholar]
  26. Skinner M. A., Siddell S. G. 1985; Coding sequence of coronavirus MHV-JHM mRNA 4. Journal of General Virology 66:593–596
    [Google Scholar]
  27. Skinner M. A., Ebner D., Siddell S. G. 1985; Coronavirus MHV-JHM mRNA 5 has a sequence arrangement which potentially allows translation of a second, downstream open reading frame. Journal of General Virology 66:581–592
    [Google Scholar]
  28. Spaan W. J. M., Rottier P. J. M., Horzinek M. C., Van Der Zeijest B. A. M. 1981; Isolation and identification of virus-specific mRNAs in cells infected with mouse hepatitis virus (MHV-A59). Virology 108:424–434
    [Google Scholar]
  29. Spaan W. J. M., Delius H., Skinner M. A., Armstrong J., Rottier P. J. M., Smeekens S., Van Der Zeijst B. A. M., Siddell S. G. 1983; Coronavirus mRNA synthesis involves fusion of non-contiguous sequences. EMBO Journal 2:1839–1844
    [Google Scholar]
  30. Spaan W. J. M., Delius H., Skinner M., Armstrong J., Rottier P. J. M., Smeekens S., Siddell S. G., Van Der Zeijst B. A. M. 1984; Transcription strategy of coronaviruses: fusion of non-contiguous sequences during mRNA synthesis. In Molecular Biology and Pathogenesis of Coronaviruses pp 173–186 Rottier P. J. M., Van der Zeijst B. A. M., Spaan W. J. M., Horzinek M. C. Edited by New York: Plenum Press;
    [Google Scholar]
  31. Stern D. F., Kennedy S. I. T. 1980; Coronavirus multiplication strategy. I. Identification and characterization of virus-specified RNA. Journal of Virology 34:665–674
    [Google Scholar]
  32. Stern D. F., Sefton B. M. 1984; Coronavirus multiplication: location of genes for virion proteins on the avian infectious bronchitis virus genome. Journal of Virology 50:22–29
    [Google Scholar]
  33. Sturman L. S., Holmes K. V. 1983; The molecular biology of coronaviruses. Advances in Virus Research 28:35–112
    [Google Scholar]
  34. Ward J. M. 1970; Morphogenesis of a virus in cats with experimental feline infectious peritonitis. Virology 41:191–194
    [Google Scholar]
  35. Weiss R. C., Scott F. W. 1981a; Pathogenesis of feline infectious peritonitis: pathologic changes and immunofluorescence. American Journal of Veterinary Research 42:2036–2048
    [Google Scholar]
  36. Weiss R. C., Scott F. W. 1981b; Antibody-mediated enhancement of disease in feline infectious peritonitis: comparisons with Dengue hemorrhagic fever. Comparative Immunology, Microbiology and Infective Diseases 4:175–189
    [Google Scholar]
  37. Zook B. C., King N. W., Robinson R. L., Mccombs H. L. 1968; Ultrastructural evidence for the viral etiology of feline infectious peritonitis. Pathologia veterinaria 5:91–95
    [Google Scholar]
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