A coxsackievirus A10 strain, isolated from a clinical specimen from a patient with pharyngitis, was characterized with respect to its growth properties in dilferent cultured cells and at different incubation temperatures. This virus multiplied within cultured cells and produced cytopathogenic effects, whereas a prototype strain of coxsackievirus A10 did not. The isolate multiplied efficiently in cultured cells at 37 °C but its replication was markedly restricted at 32 °C. Temperature shift experiments indicated that the cold-sensitive event affected the late function(s) of the virus.
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