1887

Abstract

SUMMARY

Mouse thymic virus (MTV) is a naturally occurring herpesvirus of mice which produces persistent infection in salivary glands. No transmission study has been reported previously. In the present work, transmissibility of MTV has been studied by close contact between cage-mates, by the transplacental route from experimentally infected pregnant mice to their foetuses at term or delivered by Caesarean section and by nursing mothers to their sucklings. Transmission of MTV was detected between cage-mates after a long period of contact. The virus was also recovered from newborns nursed by infected mothers inoculated 1 day post-delivery. However, no transmission was detected in the foetuses following infection of mothers at different stages of pregnancy.

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/content/journal/jgv/10.1099/0022-1317-68-4-1173
1987-04-01
2022-01-22
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References

  1. Cohen P. L., Cross S. S., Mosier D. E. 1975; Immunological effects of neonatal infection with mouse thymic virus. Journal of Immunology 155:706–710
    [Google Scholar]
  2. Collins M. J. Jr Parker J. C. 1972; Murine virus contaminants of leukemia viruses and transplantable tumors. Journal of the National Cancer Institute 49:1139–1143
    [Google Scholar]
  3. Cross S. S., Morse H. C. III Asofsky R. 1976; Neonatal infection with mouse thymic virus: differential effects on T cell mediating the graft-versus-host reaction. Journal of Immunology 117:635–638
    [Google Scholar]
  4. Cross S. S., Parker J. C., Rowe W. P. 1979; Biology of mouse thymic virus, a herpesvirus of mice, and the antigenic relationship to mouse cytomegalovirus. Infection and Immunity 26:1186–1195
    [Google Scholar]
  5. Rowe W. p., Capps W. I. 1961; A new mouse virus causing necrosis of the thymus in newborn mice. Journal of Experimental Medicine 113:831–844
    [Google Scholar]
  6. Wood B. A., Dutz W., Cross S. S. 1981; Neonatal infection with mouse thymic virus: spleen and lymph node necrosis. Journal of General Virology 57:139–147
    [Google Scholar]
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