A Major Phosphoprotein of Cells Infected with Pseudorabies Virus Is Phosphorylated by Cellular Casein Kinase II Free

Abstract

SUMMARY

Endogenous protein phosphorylation was studied in extracts of hamster fibroblasts infected with pseudorabies virus. The major phosphorylation was detected quite late in infection and involved an acidic protein of 62000. It was catalysed by an enzyme activity with the properties of cellular casein kinase II. Two-dimensional gel analysis was used to demonstrate that this same protein was also phosphorylated The phosphoprotein was detected in mature virions and is most likely viral in origin.

Keyword(s): phosphoprotein , protein kinases and PRV
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/content/journal/jgv/10.1099/0022-1317-68-4-1159
1987-04-01
2024-03-29
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