@article{mbs:/content/journal/jgv/10.1099/0022-1317-68-1-115, author = "Graham, A. and Kudesia, G. and Allen, A. M. and Desselberger, U.", title = "Reassortment of Human Rotavirus Possessing Genome Rearrangements with Bovine Rotavirus: Evidence for Host Cell Selection", journal= "Journal of General Virology", year = "1987", volume = "68", number = "1", pages = "115-122", doi = "https://doi.org/10.1099/0022-1317-68-1-115", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-68-1-115", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "SUMMARY Mixed infections of secondary rhesus monkey kidney cells with human rotaviruses carrying rearranged genomes and with bovine rotavirus yielded a high percentage of reassortants. The genotypes of 511 plaque-purified clones raised in either MA104 or BSC-1 cells have been determined and the frequencies of different genotypes have been calculated. It was found that (i) reassortants did not emerge at random; (ii) there was non-random association of certain genes; (iii) the cell line used to isolate reassortants influenced the result, i.e. host cell factors had a selective effect on a recombinational mixture.", }