RT Journal Article SR Electronic(1) A1 Wleklik, Marek A1 Levy, Stuart B. A1 Łuczak, Mirosław A1 Najjar, Victor A.YR 1986 T1 Suppression of Friend Virus-induced Leukaemia in Mice by Tuftsin JF Journal of General Virology, VO 67 IS 9 SP 2001 OP 2004 DO https://doi.org/10.1099/0022-1317-67-9-2001 PB Microbiology Society, SN 1465-2099, AB Summary A significant decrease in mortality was observed when 25 µg of the tetrapeptide tuftsin was given to DBA/2J mice 5 days before infection with Friend leukaemia virus (FLV). The same effect was observed when tuftsin was given 5 days before and twice a week for 3 weeks after FLV infection. No effect was observed when the same amount of tuftsin was given 1 day before infection. A 5 µg dose of tuftsin given 5 days before and twice-weekly for 3 weeks had no effect on leukaemia induced by FLV infection. These findings showed that time and dosage were critical to the protective effect of tuftsin against virus-induced leukaemia., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-67-9-2001