1887

Abstract

Summary

Three disulphide cross-bridged glycoprotein complexes were immunoprecipitated from purified human cytomegalovirus envelopes using a monoclonal antibody with a specificity for a glycoprotein of mol. wt. 52 × 10. These complexes were isolated by electroelution after polyacrylamide gel electrophoresis (PAGE) under non-reducing conditions. Compositional analysis of each complex by PAGE under reducing conditions showed that at least two distinct complexes,one containing glycoproteins with mol. wt. of 52 × 10 and 95 × 10 and the other with glycoproteins of 52 × 10 and 130 × 10, were present. The results obtained indicated that one of these complexes could also exist as a dimer.

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/content/journal/jgv/10.1099/0022-1317-67-7-1469
1986-07-01
2022-01-27
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