@article{mbs:/content/journal/jgv/10.1099/0022-1317-67-7-1315, author = "Rose, D. S. C. and Shriver, K. and Latchman, D. S. and Lathangue, N. B.", title = "A Filamentous Distribution for the Herpes Simplex Virus Type 2-encoded Major DNA-binding Protein", journal= "Journal of General Virology", year = "1986", volume = "67", number = "7", pages = "1315-1325", doi = "https://doi.org/10.1099/0022-1317-67-7-1315", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-67-7-1315", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "HSV-2", keywords = "cytoskeleton", keywords = "DNA-binding protein", abstract = "Summary Monoclonal antibodies reacting with the herpes simplex virus (HSV)-encoded major DNA-binding protein defined an intracellular filamentous network. This network was associated predominantly with the infected cell nucleus and occurred in cells infected with HSV type 2. It did not co-distribute with microfilaments, microtubules or intermediate filaments, and DNA synthesis was required for its formation. We suggest explanations for the occurrence and function of this novel filamentous network structure.", }