1887

Abstract

Summary

Description of the interactions between bovine herpesvirus type 1 (BHV-1) and cattle was performed by the method known as kinetic logic. This logical formalization uses variables with two possible values, 1 and 0, which tell whether an element is present or not at a significant level. To each variable is associated a function which tells if the element is being produced at a significant rate. The temporal relation between a variable and its associated function is given by specific time delays. The BHV-1 infection system is described by a set of five logical equations which tell in what conditions each function is on or off. The five functions are: , development of viral multiplication; , development of reactivation of the latent virus; , development of an immune response; , establishment of the viral genome; , development of a memory of a first immune response. Several examples are detailed in a dynamic analysis, in connection with known experimental data.

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1986-05-01
2021-10-28
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