1887

Abstract

Summary

A DNA polymerase induced by virus (OMV) was isolated from cultured salmon cells infected with OMV using sequential ion-exchange column chromatography steps. The properties of the OMV polymerase were compared to those of human cytomegalovirus (HCMV) polymerase and polymerase alpha from cherry salmon (masu salmon, ) testes. OMV polymerase was clearly distinguished from the other polymerases by its optimum temperature for enzyme activity, 25 °C. In an investigation of the effects of phosphonoacetic acid and aphidicolin, OMV polymerase was found to be more resistant to both drugs than HCMV polymerase.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-67-2-405
1986-02-01
2021-10-22
Loading full text...

Full text loading...

/deliver/fulltext/jgv/67/2/JV0670020405.html?itemId=/content/journal/jgv/10.1099/0022-1317-67-2-405&mimeType=html&fmt=ahah

References

  1. Boezi J. A., Lee L. F., Blakesley R. W., Koening M., Towele H. C. 1974; Marek’s disease herpesvirus-induced DNA polymerase. Journal of Virology 14:1209–1219
    [Google Scholar]
  2. Huang E-S. 1975; Human cytomegalovirus. III. Virus induced DNA polymerase. Journal of Virology 16:298–310
    [Google Scholar]
  3. Keir H. M., Gold E. 1963; Deoxyribonucleic acid nucleotidyltransferase and deoxyribonuclease from cultured cells infected with herpes simplex virus. Biochimica et biophysica acta 72:263–276
    [Google Scholar]
  4. Kimura T., Yoshimizu M., Tanaka M., Sannohe H. 1981a; Studies on a new virus (OMV) from Oncorhynchus masou. I. Characteristics and pathogenicity. Fish Pathology 15:143–147
    [Google Scholar]
  5. Kimura T., Yoshimizu M., Tanaka M. 1981b; Studies on a new virus (OMV) from Oncorhynchus masou. II. Oncogenic nature. Fish Pathology 15:149–153
    [Google Scholar]
  6. Knopf K-W. 1979; Properties of herpes simplex virus DNA polymerase and characterization of its associated exonuclease activity. European Journal of Biochemistry 98:231–244
    [Google Scholar]
  7. Lannan C. N., Winton J. R., Fryer J. L. 1984; Fish cell lines: establishment and characterization of nine cell lines from salmonids. In Vitro 20:671–676
    [Google Scholar]
  8. Mar E-C., Huang E-S. 1979; Comparative study of herpes group virus-induced DNA polymerase. Intervirology 12:73–83
    [Google Scholar]
  9. Mar E-C., Huang Y-S., Huang E-S. 1978; Purification and characterization of varicella-zoster virus-induced DNA polymerase. Journal of Virology 26:249–256
    [Google Scholar]
  10. Miller R. L., Rapp F. 1976; Distinguishing cytomegalovirus, mycoplasma, and cellular DNA polymerases. Journal of Virology 20:564–569
    [Google Scholar]
  11. Miller R. L., Rapp F. 1977; Varicella-zoster virus-induced DNA polymerase. Journal of General Virology 36:515–524
    [Google Scholar]
  12. Miller R. L., Glaser R., Rapp F. 1977; Studies of an Epstein–Barr virus-induced DNA polymerase. Virology 76:495–502
    [Google Scholar]
  13. Nishiyama Y., Maeno K., Yoshida S. 1983; Characterization of human cytomegalovirus-induced DNA polymerase and the associated 3ʹ -to-5ʹ exonuclease. Virology 124:221–231
    [Google Scholar]
  14. O’hare P., Honess R. W. 1983; Evidence for a herpesvirus saimiri-specified DNA polymerase activity which is aphidicolin-resistant and phosphonoacetate-sensitive. Journal of General Virology 64:1013–1024
    [Google Scholar]
  15. Ooka T., Lenoir G., Daillie J. 1979; Characterization of an Epstein–Barr virus-induced DNA polymerase. Journal of Virology 29:1–10
    [Google Scholar]
  16. Ostrander M., Cheng Y-C. 1980; Properties of herpes simplex virus type 1 and type 2 DNA polymerase. Biochimica et biophysica acta 609:232–245
    [Google Scholar]
  17. Papas T. S., Dahlberg J. E., Sonstegard R. A. 1976; Type C virus in lymphosarcoma in northern pike (Esox lucius). Nature, London 261:506–508
    [Google Scholar]
  18. Powell K. L., Purifoy D. J. M. 1977; Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase. Journal of Virology 24:618–626
    [Google Scholar]
  19. Purifoy D. J. M. 1975/6; Comparison of DNA polymerase activities induced by herpes simplex virus type 1 and 2. Intervirology 6:356–366
    [Google Scholar]
  20. Weissbach A., Hong S-C. L., Aucker J., Muller R. 1973; Characterization of herpes simplex virus-induced deoxyribonucleic acid polymerase. Journal of Biological Chemistry 248:6270–6277
    [Google Scholar]
  21. Yamaguchi M., Matsukagi A., Takahashi T. 1980; Chick embryo DNA polymerase γ: purification and structural analysis of nearly homogeneous enzyme. Journal of Biological Chemistry 2557002–7009
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-67-2-405
Loading
/content/journal/jgv/10.1099/0022-1317-67-2-405
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error