1887

Abstract

Summary

Persistent and latent Japanese encephalitis virus (JEV) infection was studied in pregnant and non-pregnant mice. Following intraperitoneal inoculation into pregnant mice JEV persisted for 16 weeks in contrast to 4 weeks in non-pregnant mice. This was followed by a higher frequency of latent infection in pregnant mice. The virus could be reactivated during pregnancy or by cyclophosphamide treatment, the latter being more effective.

Keyword(s): JEV , latency , persistence and reactivation
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1986-02-01
2024-11-12
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References

  1. Chaturvedi U. C., Tandon P., Mathur A. 1977; Effect of immunosuppression on dengue virus infection in mice. Journal of General Virology 36:449–458
    [Google Scholar]
  2. Chaturvedi U. C., Mathur A., Chandra A., Das S. K., Tandon H. O., Singh U. K. 1980; Transplacental infection with Japanese encephalitis virus. Journal of Infectious Diseases 141:712–715
    [Google Scholar]
  3. Clarke D. H., Casals J. 1958; Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. American Journal of Tropical Medicine & Hygiene 7:561–573
    [Google Scholar]
  4. Coetzer J. A. W., Barnard B. J. H. 1977; Hydrops amnii in sheep associated with hydroencephaly and arthrogrypasis with Wesselsborn disease and Rift Valley fever viruses as aetiological agents. Onderstepoort Journal of Veterinary Research 44:119–126
    [Google Scholar]
  5. Indian Council Of Medical Research (1980 Japanese Encephalitis in India 2nd edn New Delhi: Indian Council of Medical Research;
    [Google Scholar]
  6. Ito T., Saito S. 1952; Susceptibility of bats to Japanese B encephalitis virus. Japanese Journal of Bacteriology 7:612–622 (in Japanese)
    [Google Scholar]
  7. Khatib R., Khatib G., Chason J. L., Lerner A. M. 1983; Alteration in coxsackie virus B4 heart muscle disease in ICR Swiss mice by anti-thymocyte serum. Journal of General Virology 64:231–261
    [Google Scholar]
  8. Mahy B. W. J. 1985; Strategies of virus persistence. British Medical Bulletin 41:50–55
    [Google Scholar]
  9. Mathur A., Arora K. L., Chaturvedi U. C. 1981; Congenital infection of mice with Japanese encephalitis virus. Infection and Immunity 34:26–29
    [Google Scholar]
  10. Mathur A., Arora K. L., Chaturvedi U. C. 1982; Transplacental Japanese encephalitis virus (JEV) infection in mice during consecutive pregnancies. Journal of General Virology 59:213–217
    [Google Scholar]
  11. Mathur A., Arora K. L., Chaturvedi U. C. 1983; Host defence mechanisms against Japanese encephalitis virus infection in mice. Journal of General Virology 64:805–811
    [Google Scholar]
  12. Mathur A., Rawat S., Chaturvedi U. C. 1984; Suppressor T cells for delayed type hypersensitivity to Japanese encephalitis virus. Immunology 52:395–402
    [Google Scholar]
  13. Mathur A., Tandon H. O., Mathur K. R., Sarkari N. B. S., Singh U. K., Chaturvedi U. C. 1985; Japanese encephalitis virus infection during pregnancy. Indian Journal of Medical Research 81:9–12
    [Google Scholar]
  14. Mims C. A. 1982; Role of persistence in viral pathogenesis. In Virus Persistence pp. 1–13 Edited by Mahy J. B. W., Minson A. C., Darby G. K. Cambridge: Cambridge University Press;
    [Google Scholar]
  15. Rager-Zisman B., Allison A. C. 1973; Effects of immunosuppression on Coxsackie B-3 virus infection in mice, and passive protection by circulating antibody. Journal of General Virology 19:339–351
    [Google Scholar]
  16. Rehacek J. 1968; Persistent infection of mosquito cells grown in vitro with Murray valley encephalitis and Japanese encephalitis viruses. Acta virologica 12:340–346
    [Google Scholar]
  17. Schmaljohn C. S., Blair C. D. 1979; Clonal analysis of mammalian cell cultures persistently infected with Japanese encephalitis virus. Journal of Virology 31:816–822
    [Google Scholar]
  18. Shiraki H. 1970; Japanese encephalitis. In Clinical Virology pp 155–175 Edited by Debre R., Celers J. Philadelphia: W. B. Saunders;
    [Google Scholar]
  19. Shultz G., Delay P. D. 1955; Losses in new born lambs associated with blue tongue vaccination of pregnant ewes. Journal of the American Veterinary Medical Association 127:224–226
    [Google Scholar]
  20. Stroop W. G., Baringer J. R. 1982; Persistent, slow and latent viral infections. Progress in Medical Virology 28:1–43
    [Google Scholar]
  21. Walker D. L., Padgett B. L. 1983; Progressive multifocal leukoencephalopathy. In Comprehensive Virology vol 18 pp. 161–163 Edited by Fraenkel-Conrat H., Wagner R. R. New York: Plenum Press;
    [Google Scholar]
  22. Wildy P., Gell P. G. H. 1985; The host response to herpes simplex virus. British Medical Bulletin 4186–91
    [Google Scholar]
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