RT Journal Article SR Electronic(1) A1 Villaverde, Antonio A1 Guerrero, Ricardo A1 Barbé, JordiYR 1986 T1 Effect of P22-mediated Receptor Release and of Phage DNA Injection on Cell Viability of Salmonella typhimurium JF Journal of General Virology, VO 67 IS 11 SP 2561 OP 2564 DO https://doi.org/10.1099/0022-1317-67-11-2561 PB Microbiology Society, SN 1465-2099, AB Summary Infection with u.v.-inactivated P22 bacteriophage at multiplicities higher than 30 caused a decrease in Salmonella typhimurium viability without cell lysis. Neither the action of the endoglycosidase of the P22 virion on the lipopolysaccharide of S. typhimurium nor the concomitant release of cell wall components was responsible for m.o.i.-dependent cell death. Using both free P22 tails and u.v.-inactivated P22, we have shown that p9 tail protein activity has no effect either on the integrity of host cells or on cell viability. Our results show that cell death is due to the injection of the u.v.-inactivated P22 DNA., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-67-11-2561