1887

Abstract

SUMMARY

Infection of mouse embryo fibroblasts in G or S phase with encephalomyocarditis virus gave different kinetics of viral RNA synthesis. In S phase cells, RNA synthesis was faster and reached higher levels than in G cells. Virus-specified proteins were fewer in G cells than in S cells during the early stage of the infection and c.p.e. in G cells appeared about 4 h later than in S cells. Addition of a cellular factor with ability to affect cell conformation had an inhibitory effect on viral RNA synthesis.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-66-7-1501
1985-07-01
2024-04-23
Loading full text...

Full text loading...

/deliver/fulltext/jgv/66/7/JV0660071501.html?itemId=/content/journal/jgv/10.1099/0022-1317-66-7-1501&mimeType=html&fmt=ahah

References

  1. Benecke B. J., Ben-Ze’ev A., Penman S. 1978; The control of mRNA translation and turnover in suspended and reattached anchorage-dependent fibroblasts. Cell 14:931–939
    [Google Scholar]
  2. Ben-Ze’ev A., Farmer S. R., Penman S. 1980; Protein synthesis requires cell-surface contact while nuclear events respond to cell shape in anchorage-dependent fibroblasts. Cell 21:365–372
    [Google Scholar]
  3. Bourgeade M. F., Chany C. 1976; Inhibition of interferon action by cytochalasin B, colchicine and vinblastine. Proceedings of the Society for Experimental Biology and Medicine 153:501–504
    [Google Scholar]
  4. Bourgeade M. F., Chany C. 1979; Effect of sodium butyrate on the antiviral and anticellular action of interferon in normal and MSV-transformed cells. International Journal of Cancer 24:314–318
    [Google Scholar]
  5. Brownson J. M., Mahy B. W. J. 1979; Productive influenza virus infection of synchronized chick embryo fibroblast cells. Journal of General Virology 42:579–588
    [Google Scholar]
  6. Cervera M., Dreyfuss G., Penman S. 1981; Messenger RNA is translated when associated with the cytoskeletal framework in normal and VSV-infected HeLa cells. Cell 23:113–120
    [Google Scholar]
  7. Eremenko T., Benedetto A., Volpe P. 1972; Poliovirus replication during HeLa cell life cycle. Nature New Biology 237:114–116
    [Google Scholar]
  8. Farmer S. R., Ben-Ze’ev A., Benecke B. J., Penman S. 1978; Altered translatability of messenger RNA from suspended anchorage-dependent fibroblasts: reversal upon cell attachment to a surface. Cell 15:627–637
    [Google Scholar]
  9. Folkman J., Moscona A. 1978; Role of cell shape in growth control. Nature, London 273:345–349
    [Google Scholar]
  10. Joseph B. S., Oldstone M. B. A. 1974; Antibody induced re-distribution of measles virus antigens on the cell surface. Journal of Immunology 113:1205–1209
    [Google Scholar]
  11. Kraft V., Tischer I. 1978; Cell cycle dependent multiplication of avian adenoviruses in chicken embryo fibroblasts. Archives of Virology 57:243–254
    [Google Scholar]
  12. Laemmli U. K. 1970; Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, London 221:680–685
    [Google Scholar]
  13. Lawrence W. C. 1971; Evidence for a relationship between equine abortus (herpes) virus deoxyribonucleic acid synthesis and the S phase of the KB cell mitotic cycle. Journal of Virology 7:736–748
    [Google Scholar]
  14. Lomniczi B., Bosch F. X., Hay A. J., Skehel J. J. 1977; Influenza virus infection of a cell-cycle mutant of Chinese hamster ovary cells. Journal of General Virology 35:187–190
    [Google Scholar]
  15. Long W. F., Cooper R. J. 1974; Infection of synchronised cells by influenza virus. Microbiologica 10A:45–53
    [Google Scholar]
  16. Mallucci L., Edwards B. 1982; Influence of the cytoskeleton on the expression of a mouse hepatitis virus (MHV-3) in peritoneal macrophages: acute and persistent infection. Journal of General Virology 63:717–721
    [Google Scholar]
  17. Mallucci L., Dunn M., Wells V., Delia D. 1980; A cell cycle study of the effects of ConA on synchronised mouse embryo fibroblasts: arrest of two specific stages of the cycle and dissociation between uptake of thymidine and DNA synthesis. Journal of Cell Sciences 46:353–363
    [Google Scholar]
  18. Mallucci L., Rasbridge S., Wells V. 1983; Cell cycle study on the effect of interferon on synchronised mouse embryo fibroblasts. Journal of Interferon Research 3:181–189
    [Google Scholar]
  19. Menna J. H., Collins A. R., Flanagan T. D. 1975; Characterisation of an in vitro persistent-state measles infection. I. Establishment and virological characteristics of the BGM/MV cell line. Infection and Immunity 11:152–158
    [Google Scholar]
  20. Pages J., Monteuil S., Stehelin D., Fiszman M., Marx M., Girard M. 1973; Relationship between replication of simian virus 40 DNA and specific events of the host cell cycle. Journal of Virology 12:99–107
    [Google Scholar]
  21. Panem S. 1977; Cell cycle dependent inhibition of Kirsten murine sarcoma virus release by cytochalasin B. Virology 76:146–151
    [Google Scholar]
  22. Reeve P., Poste G., Alexander D. 1975; Cell surface changes in Newcastle disease virus-infected cells. In Negative Strand Viruses vol 2: pp 859–873 Edited by Mahy B. W. J., Barry R. D. London & New York: Academic Press;
    [Google Scholar]
  23. Rhode S. L. 1973; Replication process of the parvovirus H-l. I. Kinetics in a parasynchronous cell system. Journal of Virology 11:856–861
    [Google Scholar]
  24. Rott R., Becht H., Hammer C., Klenk H. D., Scholtissek C. 1975; Changes in surface of host cell after infection with enveloped viruses. In Negative Strand Viruses vol 2: pp 843–873 Edited by Mahy B. W. J., Barry R. D. London & New York: Academic Press;
    [Google Scholar]
  25. Siegl G., Gautschi M. 1973; The multiplication of parvovirus Lu III in a synchronised culture system. I. Optimum condition for virus replication. Archiv für die gesamte Virusforschung 40:105–118
    [Google Scholar]
  26. Suarez M., Contreras G., Fridlender B. 1973; Multiplication of coxsackie B, virus in synchronised HeLa cells. Journal of Virology 16:1337–1339
    [Google Scholar]
  27. Temin H. M. 1967; Studies on carcinogenesis by avian sarcoma virus. V. Requirement for new DNA synthesis and for cell division. Journal of Cellular and Comparative Physiology 69:53–64
    [Google Scholar]
  28. Thorne H. V. 1973; Cyclic variation in the susceptibility of Balb-c 3T3 cells to polyoma virus. Journal of General Virology 18:163–169
    [Google Scholar]
  29. Weiss R., Teich N., Varmus H., Coffin J. (editors) 1982 RNA Tumor Viruses New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  30. Wells V., Mallucci L. 1978; Determination of cell form in cultured fibroblasts. Experimental Cell Research 116:301–312
    [Google Scholar]
  31. Wells V., Mallucci L. 1983; Properties of a cell growth inhibitor produced by mouse embryo fibroblasts. Journal of Cell Physiology 117:148–154
    [Google Scholar]
  32. Wittelsberger S. C., Kleene K., Penman S. 1981; Progressive loss of shape-responsive metabolic controls in cells with increasingly transformed phenotypes. Cell 24:839–866
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-66-7-1501
Loading
/content/journal/jgv/10.1099/0022-1317-66-7-1501
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error