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The amounts of chronic bee-paralysis virus associate (CPVA) produced in bees injected with purified chronic bee-paralysis virus (CPV) were negatively associated with the amounts, lengths of particles and maximum sedimentation coefficients of CPV. The ratio of the amounts of CPV/CPVA varied widely between individuals, but more CPVA was produced and CPV/CPVA ratios were smaller when CPVA was injected with the CPV preparations than when the latter were injected alone. The multiplication of the RNAs of CPV and of CPVA were also negatively correlated. The nature of the relationship between CPV and CPVA and the packaging arrangement of CPV RNA are discussed.
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