1887

Abstract

SUMMARY

The steps from the precursor to the processed forms of a secreted glycoprotein (gA) of Marek′s disease virus (MDV) and of herpesvirus of turkeys (HVT) were examined by two-dimensional gel electrophoresis of immunoprecipitates from the cell lysate and medium of infected cultures with monoclonal antibodies. Differences between MDV-and HVT-gA were particularly observed in isoelectric points of the glycosylated or unglycosylated precursor forms.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-66-5-1131
1985-05-01
2022-11-27
Loading full text...

Full text loading...

/deliver/fulltext/jgv/66/5/JV0660051131.html?itemId=/content/journal/jgv/10.1099/0022-1317-66-5-1131&mimeType=html&fmt=ahah

References

  1. Akiyama Y., Kato S. 1974; Two cell lines from lymphomas of Marek’s disease. Biken Journal 17:105–116
    [Google Scholar]
  2. Chirgwin J. M., Przybyla A. E., Macdonald R. J., Rutter W. J. 1979; Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294–5299
    [Google Scholar]
  3. Churchill A. E., Chubb R. C., Baxendale W. 1969; The attenuation, with loss of oncogenicity, of the herpes-type virus of Marek’s disease (strain HPRS-16) on passage in cell culture. Journal of General Virology 4:557–564
    [Google Scholar]
  4. Gahmberg G. G., Jokinen M., Karhi K. K., Anderson L. C. 1980; Effect of tunicamycin on the biosynthesis of the major human red cell sialoglycoprotein, glycophorin A, in the leukemia cell line K562. Journal of Biological Chemistry 255:2169–2175
    [Google Scholar]
  5. Gibbs C. P., Nazerian K., Velicer L. F., Kung H. J. 1984; Extensive homology exists between Marek disease herpesvirus and its vaccine virus, herpesvirus of turkey. Proceedings of the National Academy of Sciences U.S.A 81:3365–3369
    [Google Scholar]
  6. Glaubiger C., Nazerian K., Velicer L. F. 1983; Marek′s disease herpesvirus. IV. Molecular characterization of Marek’s disease herpesvirus A antigen. Journal of Virology 45:1228–1234
    [Google Scholar]
  7. Hirai K., Ikuta K., Kato S. 1979; Comparative studies on Marek’s disease virus and herpesvirus of turkey DNAs. Journal of General Virology 45:119–131
    [Google Scholar]
  8. Hirai K., Ikuta K., Maotani K., Kato S. 1984; Evaluation of DNA homology of Marek’s disease virus, herpesvirus of turkeys and Epstein-Barr virus under varied stringent hybridization conditions. Journal of Biochemistry 95:1215–1218
    [Google Scholar]
  9. Ikuta K., Nishi Y., Kato S., Hirai K. 1981; Immunoprecipitation of Marek’s disease virus-specific polypeptides with chicken antibodies purified by affinity chromatography. Virology 114:277–281
    [Google Scholar]
  10. Ikuta K., Honma H., Maotani K., Ueda S., Kato S., Hirai K. 1982; Monoclonal antibodies specific to and cross-reactive with Marek’s disease virus and herpesvirus of turkeys. Biken Journal 25:171–175
    [Google Scholar]
  11. Ikuta K., Ueda S., Kato S., Hirai K. 1983a; Most virus-specific polypeptides in cells productively infected with Marek′s disease virus or herpesvirus of turkeys possess cross-reactive determinants. Journal of General Virology 64:961–965
    [Google Scholar]
  12. Ikuta K., Ueda S., Kato S., Hirai K. 1983b; Monoclonal antibodies reactive with the surface and secreted glycoproteins of Marek’s disease virus and herpesvirus of turkeys. Journal of General Virology 64:2597–2610
    [Google Scholar]
  13. Ikuta K., Ueda S., Kato S., Hirai K. 1984a; Identification with monoclonal antibodies of glycoproteins of Marek’s disease virus and herpesvirus of turkeys related to virus neutralization. Journal of Virology 49:1014–1017
    [Google Scholar]
  14. Ikuta K., Nakajima K., Ueda S., Kato A., Hirai K. 1984b; Studies on the cross-reaction between Marek’s disease virus and herpesvirus of turkeys using monoclonal antibodies to major virus-specific polypeptides. Archives of Virology 81:337–343
    [Google Scholar]
  15. Kaschka-Dierich C., Bornkamm G. W., Thomssen R. 1979; No homology detectable between Marek’s disease virus (MDV) DNA and herpesvirus of turkeys (HVT) DNA. Medical Microbiology and Immunology 165:223–239.
    [Google Scholar]
  16. Lee L. F., Liu X., Witter R. L. 1983; Monoclonal antibodies with specificity for three different serotypes of Marek′s disease virus in chickens. Journal of Immunology 130:1003–1006
    [Google Scholar]
  17. Lee Y. -S., Tanaka A., Silver S., Smith M., Nonoyama M. 1979; Minor DNA homology between herpesvirus of turkey and Marek’s disease virus?. Virology 93:277–280
    [Google Scholar]
  18. Long P. A., Kaveh-Yamini P., Vilicer L. F. 1975; Marek’s disease herpesvirus. I. Production and preliminary characterization of Marek’s disease herpesvirus A antigen. Journal of Virology 15:1182–1191
    [Google Scholar]
  19. Okazaki W., Purchase H. G., Burmester B. R. 1970; Protection against Marek’s disease by vaccination with a herpesvirus of turkeys. Avian Disease 14:413–429
    [Google Scholar]
  20. Powell P. C., Payne L. N., Frazier J. A., Rennie M. 1974; T lymphoblastoid cell lines from Marek’s disease lymphomas. Nature, London 251:79–80
    [Google Scholar]
  21. Ross L. J. N., Biggs P. M., Newton A. A. 1973; Purification and properties of the ‘A’ antigen associated with Marek’s disease virus infections. Journal of General Virology 18:291–304
    [Google Scholar]
  22. Rothman J. E., Katz F. N., Lodish H. F. 1978; Glycosylation of a membrane protein is restricted to the growing polypeptide chain but is not necessary for insertion as a transmembrane protein. Cell 15:1447–1454
    [Google Scholar]
  23. Schwarz R. T., Rohrschneider J. M., Schmidt M. F. G. 1976; Suppression of glycoprotein formation of Semliki Forest, influenza, and avian sarcoma virus by tunicamycin. Journal of Virology 19:782–791
    [Google Scholar]
  24. Van Zaane D., Brinkhof J. M. A., Gielkens A. L. J. 1982; Molecular-biological characterization of Marek’s disease virus. II. Differentiation of various MDV and HVT strains. Virology 121:133–146
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-66-5-1131
Loading
/content/journal/jgv/10.1099/0022-1317-66-5-1131
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error