Amino Acid Sequences of Haemagglutinins of Influenza Viruses of the H Subtype Isolated from Horses Free

Abstract

SUMMARY

The amino acid sequence of the haemagglutinin of A/equine/Miami/63 (HN), the prototype influenza virus of the H subtype from horses, is deduced from the nucleotide sequence of virus RNA and compared with the sequences of haemagglutinins of viruses of this subtype isolated from humans [X-31 (HN)] and from birds [A/duck/Ukraine/63 (HN)] and with the sequence of the haemagglutinin of A/equine/Fontainebleau/79 (HN) a virus isolated from a recent outbreak of equine influenza. The amino acid sequence differences detected are discussed with reference to the structure of the molecules, their antigenicity and antigenic drift in influenza viruses isolated from horses.

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1985-03-01
2024-03-28
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