1887

Abstract

SUMMARY

An antiserum was produced to the oligomeric form of glycoprotein B (gB) induced by herpes simplex virus type 1 (HSV-1) strain 17. This antiserum gave a single common precipitin line in agar gel immunodiffusion with HSV-1, HSV-2, bovine mammillitis virus (BMV) and equine herpesvirus type 1 (EHV-1). It also neutralized HSV-1, HSV-2 and BMV but not EHV-1. Absorption of the antiserum with excess HSV-2 or BMV antigen resulted in an HSV-1-specific neutralizing antiserum. In immunoprecipitation, two proteins, gB and pgB, were precipitated from HSV-1- and HSV-2-infected cells and at least three from BMV- and EHV-1-infected cells. Glycoprotein B and pgB of three HSV-1 and three HSV-2 strains and the corresponding antigenically related glycoproteins of BMV- and EHV-1-infected cells were labelled with I, digested with trypsin and the resulting peptides separated by two-dimensional thin-layer chromatography or high-pressure liquid chromatography. The resulting profiles were found to be almost identical, suggesting considerable structural conservation of the peptide backbone of the antigenically related glycoproteins of these four viruses.

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1985-02-01
2021-10-22
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References

  1. Aurelian L. 1968; Demonstration by plaque reduction technique of immunologic relationship between canine herpes virus and herpes simplex virus. Proceedings of the Society for Experimental Biology and Medicine 127:485–488
    [Google Scholar]
  2. Balachandran N., Harnish D., Killington R. A., Bachetti S., Rawls W. E. 1981; Monoclonal antibodies to two glycoproteins of herpes simplex virus type 2. Journal of Virology 39:438–446
    [Google Scholar]
  3. Balachandran N., Harnish D., Rawls W. E., Bacheto S. 1982; Glycoproteins of herpes simplex virus type 2 as defined by monoclonal antibodies. Journal of Virology 44:344–355
    [Google Scholar]
  4. Baucke R. B., Spear P. G. 1979; Membrane proteins specified by herpes simplex viruses. V. Identification of an Fc-binding glycoprotein. Journal of Virology 31:779–789
    [Google Scholar]
  5. Blue W. T., Plummer G. 1973; Antigenic relationships among four herpesviruses. Infection and Immunity 7:1000–1002
    [Google Scholar]
  6. Bolton A. E., Hunter W. M. 1973; The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Biochemical Journal 133:529–539
    [Google Scholar]
  7. Brown S. M., Ritchie D. A., Subak-Sharpe J. H. 1973; Genetic studies with herpes simplex virus type 1. The isolation of temperature-sensitive mutants, their arrangement into complementation groups and recombination analysis leading to a linkage map. Journal of General Virology 18:329–346
    [Google Scholar]
  8. Bzik D. J., Fox B. A., De Luca N. A., Person S. 1984; Nucleotide sequence specifying the glycoprotein gene, gB, of herpes simplex virus type 1. Virology 133:301–314
    [Google Scholar]
  9. Cohen G. H., Katze M., Hydrean-Stern C., Eisenberg R. J. 1978; Type-common CP-1 antigen of herpes simplex virus is associated with a 59, 000 molecular-weight envelope glycoprotein. Journal of Virology 27:172–181
    [Google Scholar]
  10. Davison A. J., Wilkie N. M. 1983; Location and orientation of homologous sequences in the genomes of five herpesviruses. Journal of General Virology 64:1927–1942
    [Google Scholar]
  11. Eberle R., Courtney R. J. 1980a; Preparation and characterization of specific antisera to individual glycoprotein antigens comprising the major glycoprotein region of herpes simplex virus type 1. Journal of Virology 35:902–917
    [Google Scholar]
  12. Eberle R., Courtney R. J. 1980b; gA and gB glycoproteins of herpes simplex virus type 1: two forms of a single polypeptide. Journal of Virology 36:665–675
    [Google Scholar]
  13. Eisenberg R. J., Long D., Pereira L., Hampar B., Zweig M., Cohen G. H. 1982; Effect of monoclonal antibodies on limited proteolysis of native glycoprotein gD of herpes simplex virus type 1. Journal of Virology 41:478–488
    [Google Scholar]
  14. Ejercito P. M., Kieff E. D., Roizman B. 1968; Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells. Journal of General Virology 2:357–364
    [Google Scholar]
  15. Elder J. H., Pickett R. A., Hampton I., Lerner R. A. 1977; Radioiodination of proteins in single polyacrylamide gel slices. Journal of Biological Chemistry 252:6510–6515
    [Google Scholar]
  16. Gibson T., Stockwell P., Ginsburg M., Barrell B. 1984; Homology between two EBV early genes and HSV ribonucleotide reductase and 38K. genes. Nucleic Acids Research 12:5087–5099
    [Google Scholar]
  17. Halliburton I. W. 1980; Intertypic recombinants of herpes simplex viruses. Journal of General Virology 48:1–23
    [Google Scholar]
  18. Halliburton I. W., Randall R. E., Killington R. A., Watson D. H. 1977; Some properties of recombinants between type 1 and type 2 herpes simplex viruses. Journal of General Virology 36:471–484
    [Google Scholar]
  19. Halliburton I. W., Morse L. S., Roizman B., Quinn K. E. 1980; Mapping of the thymidine kinase genes of type 1 and type 2 herpes simplex viruses using intertypic recombinants. Journal of General Virology 49:235–253
    [Google Scholar]
  20. Hampar B., Stevens D. A., Martos L. M., Ablashi D. V., Burroughs M. A. K., Wells G. A. 1969; Correlation between the neutralising activity of human serum against herpes simplex virus and a simian herpesvirus SA8. Journal of Immunology 102:397–403
    [Google Scholar]
  21. Honess R. W., Powell K. L., Robinson D. J., Sim C., Watson D. H. 1974; Type specific and type common antigens in cells infected with herpes simplex virus type 1 and on the surfaces of naked and envelope particles of the virus. Journal of General Virology 22:159–169
    [Google Scholar]
  22. Kaplan A. S., Vatter A. E. 1959; A comparison of herpes simplex and pseudorabies viruses. Virology 7:394–407
    [Google Scholar]
  23. Kieff E., Hoyer B., Bachenheimer S., Roizman B. 1972; Genetic relatedness of type 1 and type 2 herpes simplex viruses. Journal of Virology 9:738–745
    [Google Scholar]
  24. Killington R. A., Yeo J., Honess R. W., Watson D. H., Halliburton I. W., Mumford J. 1977; Comparative analysis of the proteins and antigens of five herpesviruses. Journal of General Virology 37:297–310
    [Google Scholar]
  25. Killington R. A., Randall R. E., Yeo J., Honess R. W., Halliburton I. W., Watson D. H. 1978; Observations on antigenic relatedness between viruses of the herpes simplex ‘neutroseron’. In Oncogenesis and Herpesviruses, III pp 185–194 Edited by de The G., Henle W., Rapp F. Lyon: IARC Scientific Publications;
    [Google Scholar]
  26. Little S. P., Iofre I. T., Courtney R. I., Schaffer P. A. 1981; A virion-associated glycoprotein essential for infectivity of herpes simplex virus type 1. Virology 115:149–160
    [Google Scholar]
  27. Littler E., Yeo J., Killington R. A., Purifoy D. J. M., Powell K. L. 1981; Antigenic and structural conservation of herpesvirus DNA-binding proteins. Journal of General Virology 56:409–419
    [Google Scholar]
  28. Ludwig H., Biswal N., Bryans J. T., McCoombs R. M. 1971; Some properties of the DNA from a new equine herpesvirus. Virology 45:534–537
    [Google Scholar]
  29. Marsden H. S., Stow N. D., Preston V. G., Timbury M. C., Wilkie N. M. 1978; Physical mapping of herpes simplex virus induced polypeptides. Journal of Virology 28:624–642
    [Google Scholar]
  30. Marsden H. S., Buckmaster A., Palfreyman J. W., Hope R. G., Minson A. C. 1984; Characterisation of the 92, 000-dalton glycoprotein induced by herpes simplex virus type 2. Journal of Virology 50:547–554
    [Google Scholar]
  31. Martin W. B., Hay D., Crawford L. V., Le Bouvier G. L., Crawford E. M. 1966; Characteristics of bovine mammillitis virus. Journal of General Microbiology 45:325–332
    [Google Scholar]
  32. Mayr A., Bohm H. C., Brill J., Woychiechowskas S. 1965; Characterisierum eines Stutenabortvirus aus Polen und Vergleich mit bekannten Rhinopneumonitisvirusstammen des Pferdes. Archiv für die gesamte Virusforschung 17:216–230
    [Google Scholar]
  33. Morse L. S., Buchman T. G., Roizman B., Schaffer P. A. 1977; Anatomy of herpes simplex virus DNA. IX. Apparent exclusion of some parental DNA arrangements in the generation of intertypic (HSV-1 × HSV-2) recombinants. Journal of Virology 24:231–248
    [Google Scholar]
  34. Norrild B., Ludwig H., Rott R. 1978; Identification of a common antigen of herpes simplex virus, bovine herpes mammillitis virus, and B virus. Journal of Virology 26:712–717
    [Google Scholar]
  35. Para M. F., Baucke R. B., Spear P. G. 1980; Immunoglobulin G(Fc)-binding receptors on virions of herpes simplex virus type 1 and transfer of these receptors to the surface by infection. Journal of Virology 34:512–520
    [Google Scholar]
  36. Peake M. L., Nystrom P., Pizer L. I. 1982; Herpesvirus glycoprotein synthesis and insertion into plasma membranes. Journal of Virology 42:678–690
    [Google Scholar]
  37. Pereira L., Dondero D., Norrild B., Roizman B. 1981; Differential immunologic reactivity and processing of glycoproteins gA and gB of herpes simplex virus types 1 and 2 made in Vero and HEp-2 cells. Proceedings of the National Academy of Sciences, U. S. A 78:5202–5206
    [Google Scholar]
  38. Plummer G. 1964; Serological comparison of the herpesviruses. British Journal of Experimental Pathology 45:135–141
    [Google Scholar]
  39. Powell K. L., Buchan A., Sim C., Watson D. H. 1974; Type-specific protein in herpes simplex virus envelope reacts with neutralising antibody. Nature, London 249:360–361
    [Google Scholar]
  40. Rawls W. E., Laurel D., Melnick J. L., Glicksman J. M., Kaufman R. H. 1968; A search for viruses in smegma, premalignant and early malignant cervical tissues. The isolation of herpesviruses with distinct antigenic properties. American Journal of Epidemiology 87:647–655
    [Google Scholar]
  41. Russell W. C. 1962; A sensitive and precise plaque assay for herpes virus. Nature, London 195:1028–1029
    [Google Scholar]
  42. Ruyechan W. T., Morse L. S., Knipe D. M., Roizman B. 1979; Molecular genetics of herpes simplex virus. II. Mapping of the major viral glycoproteins and of the genetic loci specifying the social behaviour of infected cells. Journal of Virology 29:677–697
    [Google Scholar]
  43. Sarmiento M., Spear P. G. 1979; Membrane proteins specified by herpes simplex viruses. IV. Conformation of the virion glycoprotein designated VP7 (B2). Journal of Virology 29:1159–1167
    [Google Scholar]
  44. Sarmiento M., Haffey M., Spear P. G. 1979; Membrane proteins specified by herpes simplex viruses. III. Role of glycoprotein VP7 (B2) in virion infectivity. Journal of Virology 29:1149–1158
    [Google Scholar]
  45. Sim C., Watson D. H. 1973; The role of type specific and cross reacting structural antigens in the neutralization of herpes simplex virus types 1 and 2. Journal of General Virology 19:217–233
    [Google Scholar]
  46. Smith K. O. 1964; Relationship between the envelope and the infectivity of herpes simplex virus. Proceedings of the Society for Experimental Biology and Medicine 115:814–816
    [Google Scholar]
  47. Spear P. G. 1976; Membrane proteins specified by herpes simplex viruses. I. Identification of four glycoprotein precursors and their products in type 1-infected cells. Journal of Virology 17:991–1008
    [Google Scholar]
  48. Sterz H., Ludwig H., Rott R. 1973/4; Immunologic and genetic relationship between herpes simplex virus and bovine herpes mammillitis virus. Intervirology 2:1–13
    [Google Scholar]
  49. Sugino W. M., Kingsbury D. T. 1976; DNA homologies between strains of herpes simplex virus. Virology 71:605–608
    [Google Scholar]
  50. Thompson G. R., Mumford J. A., Campbell J., Griffiths L., Clapham P. 1976; Serological detection of equid herpesvirus 1 infections of the respiratory tract. British Equine Veterinary Journal 8:58–65
    [Google Scholar]
  51. Turtinen L. W., Allen G. P. 1982; Identification of the envelope surface glycoproteins of equine herpesvirus type 1. Journal of General Virology 63:481–485
    [Google Scholar]
  52. Watson D. H., Wildy P. 1969; The preparation of ‘monoprecipitin’ antisera to herpes virus specific antigens. Journal of General Virology 4:163–168
    [Google Scholar]
  53. Watson D. H., Shedden W. I. H., Elliot A., Tetsuka T., Wildy P., Bourgaux-Ramoisy D., Gold E. 1966; Virus specific antigens in mammalian cells infected with herpes simplex virus. Immunology 11:399–408
    [Google Scholar]
  54. Watson D. H., Wildy P., Harvey B. A. M., Shedden W. I. H. 1967; Serological relationships among viruses of the herpes group. Journal of General Virology 1:139–141
    [Google Scholar]
  55. Yeo J., Killington R. A., Watson D. H., Powell K. L. 1981; Studies on cross-reactive antigens in the herpesviruses. Virology 108:256–266
    [Google Scholar]
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