%0 Journal Article %A Bruns, Michael %A Lehmann-Grube, Fritz %T Lymphocytic Choriomeningitis Virus. VII. Structural Alterations of the Virion by Treatment with Proteolytic Enzymes without Loss of Infectivity %D 1984 %J Journal of General Virology, %V 65 %N 8 %P 1431-1435 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-65-8-1431 %K arenavirus %K LCM virus %K infectivity %K proteolytic treatment %I Microbiology Society, %X SUMMARY Treatment of lymphocytic choriomeningitis virus with proteolytic enzymes, hyaluronidase, and phospholipase C increased infectious titres. Biochemical analysis of bromelain- and trypsin-treated virus revealed that infectivity was high in spite of the decrease to low or undetectable levels of all viral glycoproteins as well as partial degradation of the nucleoprotein. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-65-8-1431