1887

Abstract

SUMMARY

Two stable monoclonal hybridoma cell lines secreting type-specific antibodies against the human papillomavirus type 1 (HPV-1) were isolated. The monoclonal antibodies detected HPV-1 antigens in frozen sections of HPV-1-induced warts, using immunofluorescence or immunoperoxidase techniques, and they reacted with HPV-1 particles in an immunodiffusion test. The two monoclonal antibodies recognized the major structural viral polypeptide, with a molecular weight of 54000, and a minor polypeptide, with a molecular weight of 76000, in both the dissociated viral particles and in the wart extracts.

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/content/journal/jgv/10.1099/0022-1317-65-8-1319
1984-08-01
2024-04-23
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