@article{mbs:/content/journal/jgv/10.1099/0022-1317-65-7-1225, author = "Fenwick, M. L. and McMenamin, M. M.", title = "Early Virion-associated Suppression of Cellular Protein Synthesis by Herpes Simplex Virus is Accompanied by Inactivation of mRNA", journal= "Journal of General Virology", year = "1984", volume = "65", number = "7", pages = "1225-1228", doi = "https://doi.org/10.1099/0022-1317-65-7-1225", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-65-7-1225", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "protein synthesis", keywords = "mRNA", keywords = "HSV", keywords = "shut-off", abstract = "SUMMARY Vero cells infected with herpes simplex virus in the presence of actinomycin or cycloheximide, or with u.v.-inactivated virus, suffered a rapid loss of functional mRNA as determined by translation in vitro. It is suggested that a virion-associated factor causes a structural change in the mRNA of the host cell.", }