1887

Abstract

Summary

The product of the bacteriophage T4 gene, the τ peptide, has been shown to thermally stabilize temperature-sensitive valyl-tRNA synthetase (EC 6.1.1.9). To clone the bacteriophage T4 gene, recombinant pBR322-T4 DNA molecules were used to transform CP 790302 ( ). Transformants that grew at 43.5 °C on selective medium exhibited some properties indicative of a phage-modified valyl-tRNA synthetase. The data are consistent with successful cloning of the gene and atypical modification of the valyl-tRNA synthetase in CP 790302.

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1984-04-01
2023-02-06
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