1887

Abstract

Summary

Crude interferon preparations from primary guinea-pig embryo cells infected with vesicular stomatitis virus strain T1026R1 were shown to be more sensitive to heat (37 °C), pH 2.0, and SDS than crude mouse interferon. Since the proportion of antiviral activity lost after each treatment was nearly the same, the existence of a single fraction of antiviral activity sensitive to all three treatments was suggested. Support for this possibility was given by the finding that subjecting this guinea-pig interferon to any one of the treatments rendered it insensitive to the effects of the other two.

Keyword(s): acid-labile , guinea-pig and IFN
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/content/journal/jgv/10.1099/0022-1317-65-4-843
1984-04-01
2022-01-19
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