1887

Abstract

Summary

Analysis of the neutralization of human interferon-α by the monoclonal antibody NK2 showed, by three different methods, that the avidity constant was about 10 . A small decrease in the avidity constant (and in the antibody titre) with increasing interferon concentrations was observed, suggesting that the antibody-interferon complex had a little biological activity. The antibody neutralizes the interferon by preventing the binding of interferon to susceptible cells. It does not react with human-γ, mouse-α, monkey, bovine or rabbit interferons.

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/content/journal/jgv/10.1099/0022-1317-65-3-629
1984-03-01
2019-12-06
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-65-3-629
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