1887

Abstract

Summary

The infectivity of bacteriophage LL-H was shown to be calcium-dependent. Of 10 different divalent cations screened, cadmium specifically decreased the infectivity of LL-H in the presence of calcium. At 1 to 2 m, CdCl resulted in a decrease of the burst size of about 2.5- to 4-fold. Cd was shown to reduce specifically the level of total phage DNA synthesis, resulting in a reduced progeny phage yield. Moreover, Cd had the most profound irreversible effect on progeny phage production between 20 and 60 min after LL-H infection. This paralleled the beginning of phage DNA synthesis. Possible modes of action of Cd on phage DNA replication are discussed.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-64-7-1623
1983-07-01
2019-10-18
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-64-7-1623
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error