Inactivation of Measles and Herpes Simplex Viruses by Trypan Blue Free

Abstract

SUMMARY

The dye trypan blue inhibits infection of cells in tissue culture by measles and herpes simplex viruses at concentrations in excess of 0.01% (w/v) principally by direct inactivation of the virions. The inactivation is temperature-dependent (10 times greater at 37 °C than at 4 °C) and its mechanism appears to include inhibition of virus adsorption to cells.

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1983-06-01
2024-03-29
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