1887

Abstract

SUMMARY

Leaves and callus cultures from L. were treated with a mixture of polyinosinic.policytidylic acid [poly(I).poly(C)], cyclic AMP and cyclic GMP. A new antiviral activity appearing in the treated tissues co-purified with the antiviral factor AVF. Poly(I).poly(C) can replace tobacco mosaic virus infection in the induction of AVF activity, the latter being also mediated to a certain extent by cyclic nucleotides. The kinetics of the stimulation of AVF in these studies suggests that AVF is released by a rapid activation of a pre-existing precursor, thus supporting previous results.

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1983-01-01
2021-10-26
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