The Internal Organization of the Varicella-Zoster Virus Genome Free

Abstract

SUMMARY

DNA was extracted from varicella-zoster (VZ) virions prepared in sucrose gradients. Thirty-eight molecules examined by electron microscopy were found to have a mean length of 46.7 µm. Examination of self-annealed VZV DNA molecules revealed that the virus genome was composed of a unique linear large sequence with a mol. wt. of 74.4 × 10 to 78.4 × 10, and a unique short sequence of mol. wt. approx. 9.8 × 10 flanked by inverted repeat sequences of 4.7 × 10 mol. wt.

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1982-06-01
2024-03-28
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