@article{mbs:/content/journal/jgv/10.1099/0022-1317-60-2-371, author = "Gilden, Donald H. and Shtram, Yehuda and Friedmann, Adam and Wellish, Mary and Devlin, Mary and Fraser, Nigel and Becker, Yechiel", title = "The Internal Organization of the Varicella-Zoster Virus Genome", journal= "Journal of General Virology", year = "1982", volume = "60", number = "2", pages = "371-374", doi = "https://doi.org/10.1099/0022-1317-60-2-371", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-60-2-371", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "electron microscopy", keywords = "structure", keywords = "Varicella-zoster virus", keywords = "DNA", abstract = "SUMMARY DNA was extracted from varicella-zoster (VZ) virions prepared in sucrose gradients. Thirty-eight molecules examined by electron microscopy were found to have a mean length of 46.7 µm. Examination of self-annealed VZV DNA molecules revealed that the virus genome was composed of a unique linear large sequence with a mol. wt. of 74.4 × 106 to 78.4 × 106, and a unique short sequence of mol. wt. approx. 9.8 × 106 flanked by inverted repeat sequences of 4.7 × 106 mol. wt.", }