1887

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Volume 6, Issue 2

Mise en Evidence de Certaines Activités Déshydrogénasiques dans des Fibroblastes Aviaires Transformés par le Virus du Sarcome de Rous Free

Abstract

Sommaire

Le présent travail révèle par des méthodes cytochimiques les sites d’activité des déshydrogénases lactique, isocritrique, succinique, malique et glucose-6- phosphatique dans des fibroblastes d’embryons de poulets cultives et infectés par un virus oncogéne, le virus du sarcome de Rous (souche schmidt- ruppin).

Avec ce matériel, étudié pour la premiére fois par ces méthodes, il a été constate que ces sites sont toujours plus nombreux et plus intensément colores dans les fibroblastes ‘transformes’ que dans des fibroblastes normaux en division ou infectés seulement par un virus du type ‘ Rous associated virus ’ (RAV).

Ces résultats laissent à penser que, dans le cas du sarcome de Rous de poulet et dans les conditions des experiences, la forte glycolyse des cellules malignes ne s’accompagne pas d’un affaiblissement des systèmes enzymatiques respiratoires considérés.

  • Received:
  • Accepted:
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© Society for General Microbiology Ltd 1970
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1970-02-01
2024-04-24
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Mise en Evidence de Certaines Activités Déshydrogénasiques dans des Fibroblastes Aviaires Transformés in vitro par le Virus du Sarcome de Rous
J. Gen. Virol. 6, 187 (1970); https://doi.org/10.1099/0022-1317-6-2-187
/content/journal/jgv/10.1099/0022-1317-6-2-187
/content/journal/jgv/10.1099/0022-1317-6-2-187
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