1887

Abstract

Summary

Both fowl plague and Newcastle disease viruses failed to produce interferon in chick-embryo cells because of the inhibitory effect of infection on host-cell protein synthesis. When this inhibitory effect was destroyed by ultraviolet irradiation or by hydroxylamine inactivation, interferon was formed. No virus RNA synthesis could be detected in the interferon-producing cells and it was concluded that the virus single-stranded RNA was the stimulus for interferon formation.

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/content/journal/jgv/10.1099/0022-1317-6-1-95
1970-01-01
2019-10-18
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-6-1-95
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