1887

Abstract

SUMMARY

The nucleic acid of rubella virus was shown to be RNA by the incorporation of [H]-uridine into virus particles, and by the presence of ribonuclease-sensitive material, sedimenting mainly at 38 to 40 s, in sodium dodecyl sulphate extracts of purified virus. There were at least two virus-specific RNAs in cytoplasmic extracts of BHK21 cells infected with rubella virus. One, possibly the structural RNA of the virus, was sensitive to ribonuclease and sedimented at 38 to 40 s like the RNA extracted from virus particles. The other had a heterogeneous sedimentation pattern with main peak at 20 s. It was partially resistant to ribonuclease and might be the replicative intermediate form of the RNA of rubella virus.

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1970-01-01
2022-01-25
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