%0 Journal Article %A Lebon, Pierre %A Girard, Sylvie %A Thépot, François %A Chany, Charles %T The Presence of α-Interferon in Human Amniotic Fluid %D 1982 %J Journal of General Virology, %V 59 %N 2 %P 393-396 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-59-2-393 %K IFN-α %K immune tolerance %K amniotic fluid %K foetal development %I Microbiology Society, %X SUMMARY Almost all the samples of amniotic fluid from 62 pregnant women from the 16th week to the end of the pregnancy contained detectable amounts of α-type interferon. The presence of this substance in amniotic fluid during pregnancy raises the question of the physiological significance of this finding. It is postulated that the amniotic type of α-interferon might be a product of a constitutive gene, rather than induced by latent virus infection. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-59-2-393