1887

Abstract

SUMMARY

Almost all the samples of amniotic fluid from 62 pregnant women from the 16th week to the end of the pregnancy contained detectable amounts of α-type interferon. The presence of this substance in amniotic fluid during pregnancy raises the question of the physiological significance of this finding. It is postulated that the amniotic type of α-interferon might be a product of a constitutive gene, rather than induced by latent virus infection.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-59-2-393
1982-04-01
2021-10-23
Loading full text...

Full text loading...

/deliver/fulltext/jgv/59/2/JV0590020393.html?itemId=/content/journal/jgv/10.1099/0022-1317-59-2-393&mimeType=html&fmt=ahah

References

  1. Bergeret M., Gregoire A., Chany C. 1980; Protective effect of interferon on target cells exposed to cellular cytotoxicity. Immunology 40:637–643
    [Google Scholar]
  2. Bourgeade M. F., Rousset S., Paulin D., Chany C. 1981; Reorganization of the cytoskeleton by interferon in MSV-transformed cells. Journal of Interferon Research 1:323–331
    [Google Scholar]
  3. Chany C. 1981; Interactions of interferon with the cell membrane and cytoskeleton. In Lymphokines vol 4: pp 409–431 Edited by Pick E. New York: Academic Press;
    [Google Scholar]
  4. Chany C., Vignal M. 1970; Effect of prolonged interferon treatment on mouse fibroblasts transformed by murine sarcoma virus. Journal of General Virology 7:203–210
    [Google Scholar]
  5. Chudzio T., Duc-Goiran P., Robert-Salliot B., Chany C. 1981; Unusual human α-interferons produced by the virus infected amniotic membrane. (in press)
    [Google Scholar]
  6. Fowler A. K., Reed C. D., Giron D. J. 1980; Identification of an interferon in murine placentas. Nature, London 286:266–267
    [Google Scholar]
  7. Heron I., Berg K., Cantell J. 1976; Regulation effect of interferon on T cells in vitro. Journal of Immunology 117:1370–1373
    [Google Scholar]
  8. Hirsch M. S., Ellis D. A., Black M. H., MonaCo A. P., Wood M. 1974; Immunosuppressive effects of an interferon preparation in vivo. Transplantation 17:234–236
    [Google Scholar]
  9. Lebon P., Girard S., Thepot F., Chany C. 1981; Presence constante d’interféron de type a dans les liquides amniotiques humains. Comptes rendus hebdomadaires des séances de l’Académie des sciences 293:69–71
    [Google Scholar]
  10. Lindahl P., Gresser I., Leary P., Tovey M. 1976; Interferon treatment of mice-enhanced expression of histocompatibility antigens on lymphoid cells. Proceedings of the National Academy of Sciences of the United States of America 73:1284–1287
    [Google Scholar]
  11. Mobraaten L. E., De Maeyer E., De Maeyer-Guignard J. 1973; Prolongation of allograft survival in mice by inducers of interferon. Transplantation 16:415–420
    [Google Scholar]
  12. Paucker K., Cantell K., Henle W. 1962; Quantitative studies on viral interference in suspended L cells. Effect of interfering viruses and interferon on the growth rate of cells. Virology 17:324–334
    [Google Scholar]
  13. Pfeffer L. M., Wang E., Tamm I. 1980; Interferon effect on microfilament organization, cellular fibronectin distribution and cell motility in human fibroblasts. Journal of Cell Biology 85:9–47
    [Google Scholar]
  14. Streuli M., Nagata S., Weissmann C. 1980; At least three human type α-interferons: structure of a2. Science 209:1343–1347
    [Google Scholar]
  15. Trinchieri G., Santoli D. J. 1978; Antiviral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Enhancement of human natural killer cell activity by interferon and antagonistic inhibition of susceptibility of target cells to lysis. Journal of Experimental Medicine 147:1314–1333
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-59-2-393
Loading
/content/journal/jgv/10.1099/0022-1317-59-2-393
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error