@article{mbs:/content/journal/jgv/10.1099/0022-1317-58-2-291, author = "Peiris, J. S. M. and Porterfield, J. S.", title = "Antibody-dependent Plaque Enhancement: Its Antigenic Specificity in Relation to Togaviridae", journal= "Journal of General Virology", year = "1982", volume = "58", number = "2", pages = "291-296", doi = "https://doi.org/10.1099/0022-1317-58-2-291", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-58-2-291", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "antibodies", keywords = "macrophages", keywords = "enhancement", keywords = "togavirus", abstract = "SUMMARY The antigenic specificity of antibody-dependent plaque enhancement (ADPE) on the macrophage cell line P388D1 has been investigated using viruses in the flavivirus and alphavirus genera. Whereas ADPE detected group-specific antigenic determinants in the flaviviruses, narrower specificity (type and subgroup) was seen with alphaviruses. ADPE titres correlated well with haemagglutination inhibition titres.", }