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The in vivo and in vitro synthesized immediate early (IE) polypeptides of three isolates of human cytomegalovirus (CMV) have been compared by SDS-polyacrylamide gel electrophoresis. Of the 11 IE polypeptides detected early in infection, one was very abundant and had a different apparent mol. wt. depending on the isolate. This difference may be useful in the classification of CMV into strains.
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